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    Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 [ Mus musculus (house mouse) ]

    Gene ID: 26365, updated on 24-Sep-2017
    Official Symbol
    Ceacam1provided by MGI
    Official Full Name
    carcinoembryonic antigen-related cell adhesion molecule 1provided by MGI
    Primary source
    MGI:MGI:1347245
    See related
    Ensembl:ENSMUSG00000074272 Vega:OTTMUSG00000058252
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bgp; Cc1; Hv2; Bgp1; Cea1; Cea7; Hv-2; MHVR; bb-1; C-CAM; CD66a; Cea-1; Cea-7; MHVR1; Mhv-1; mCEA1; mmCGM1; mmCGM2; mmCGM1a
    Location:
    7 A3; 7 13.84 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (25461702..25477625, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (26246721..26262644, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4732471J01 gene Neighboring gene RELT tumor necrosis factor receptor pseudogene Neighboring gene chaperonin containing Tcp1, subunit 4 (delta) pseudogene Neighboring gene predicted gene, 38967 Neighboring gene carcinoembryonic antigen-related cell adhesion molecule 2

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Toll-like receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    bile acid transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    calmodulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    filamin binding ISO
    Inferred from Sequence Orthology
    more info
     
    granulocyte colony-stimulating factor receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein dimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein tyrosine kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein tyrosine kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    virion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT virion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    virus receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT virus receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    Peyer's patch development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell-cell junction organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    common myeloid progenitor cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    granulocyte colony-stimulating factor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    homophilic cell adhesion via plasma membrane adhesion molecules IDA
    Inferred from Direct Assay
    more info
    PubMed 
    insulin catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation by host of viral genome replication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation by host of viral process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation by host of viral process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of JNK cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of bone resorption IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cytokine production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of granulocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of hepatocyte proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of interleukin-1 production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of interleukin-2 production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of lipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of osteoclast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of platelet aggregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of protein kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of vascular permeability IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation by host of viral process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of CD4-positive, alpha-beta T cell activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of CD4-positive, alpha-beta T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of CD8-positive, alpha-beta T cell activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of JNK cascade IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of MAP kinase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of NFAT protein import into nucleus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of T cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of activation-induced cell death of T cells IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of immunoglobulin secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of vasculogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of blood vessel remodeling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of endothelial cell differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of endothelial cell migration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of epidermal growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of sprouting angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    viral entry into host cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    viral process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    colocalizes_with T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    adherens junction ISO
    Inferred from Sequence Orthology
    more info
     
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    basal plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    brush border membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    lateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    carcinoembryonic antigen-related cell adhesion molecule 1
    Names
    BGP-1
    CEA-related cell adhesion molecule 1
    MHV-R
    biliary glycoprotein 1
    biliary glycoprotein D
    carcinoembryonic antigen 1
    carcinoembryonic antigen 7
    hepatitis virus (MHV-4) susceptibility
    hepatitis virus receptor
    murine hepatitis virus receptor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039185.1NP_001034274.1  carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001034274.1

      Status: VALIDATED

      Source sequence(s)
      AAHY01060000, AB236328, M77196
      Consensus CDS
      CCDS20984.1
      UniProtKB/Swiss-Prot
      P31809
      UniProtKB/TrEMBL
      Q3LFS9, Q925P3
      Related
      ENSMUSP00000096266.1, OTTMUSP00000074607, ENSMUST00000098669.7, OTTMUST00000143076
      Conserved Domains (6) summary
      cd05774
      Location:36140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00408
      Location:340401
      IGc2; Immunoglobulin C-2 Type
      cd12841
      Location:416452
      TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
      smart00410
      Location:246320
      IG_like; Immunoglobulin like
      pfam13895
      Location:242320
      Ig_2; Immunoglobulin domain
      cl11960
      Location:146235
      Ig; Immunoglobulin domain
    2. NM_001039186.1NP_001034275.1  carcinoembryonic antigen-related cell adhesion molecule 1 isoform 2 precursor

      See identical proteins and their annotated locations for NP_001034275.1

      Status: VALIDATED

      Source sequence(s)
      AAHY01060000, M77196
      Consensus CDS
      CCDS39839.1
      UniProtKB/Swiss-Prot
      P31809
      Related
      ENSMUSP00000096263.2, OTTMUSP00000074606, ENSMUST00000098666.8, OTTMUST00000143075
      Conserved Domains (6) summary
      cd05774
      Location:36140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00408
      Location:340401
      IGc2; Immunoglobulin C-2 Type
      cd12841
      Location:416452
      TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
      smart00410
      Location:246320
      IG_like; Immunoglobulin like
      pfam13895
      Location:242320
      Ig_2; Immunoglobulin domain
      cl11960
      Location:146235
      Ig; Immunoglobulin domain
    3. NM_001039187.1NP_001034276.1  carcinoembryonic antigen-related cell adhesion molecule 1 isoform 4 precursor

      See identical proteins and their annotated locations for NP_001034276.1

      Status: VALIDATED

      Source sequence(s)
      AAHY01060000, AB236329
      Consensus CDS
      CCDS85244.1
      UniProtKB/TrEMBL
      Q3LFS8
      Related
      ENSMUSP00000146066.1, OTTMUSP00000074609, ENSMUST00000206687.1, OTTMUST00000143079
      Conserved Domains (4) summary
      cd05774
      Location:36140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cd12841
      Location:236272
      TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
      smart00410
      Location:153226
      IG_like; Immunoglobulin like
      cl11960
      Location:142232
      Ig; Immunoglobulin domain
    4. NM_011926.2NP_036056.2  carcinoembryonic antigen-related cell adhesion molecule 1 isoform 3 precursor

      See identical proteins and their annotated locations for NP_036056.2

      Status: VALIDATED

      Source sequence(s)
      AAHY01060000, AB236328
      Consensus CDS
      CCDS20985.1
      UniProtKB/TrEMBL
      Q3LFS9
      Related
      ENSMUSP00000096265.1, OTTMUSP00000074608, ENSMUST00000098668.2, OTTMUST00000143077
      Conserved Domains (4) summary
      cd05774
      Location:36140
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      smart00408
      Location:160221
      IGc2; Immunoglobulin C-2 Type
      cd12841
      Location:236272
      TM_EphA1; Transmembrane domain of Ephrin Receptor A1 Protein Tyrosine Kinase
      smart00410
      Location:153226
      IG_like; Immunoglobulin like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      25461702..25477625 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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