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    Efhc1 EF-hand domain (C-terminal) containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 71877, updated on 25-May-2017
    Official Symbol
    Efhc1provided by MGI
    Official Full Name
    EF-hand domain (C-terminal) containing 1provided by MGI
    Primary source
    MGI:MGI:1919127
    See related
    Ensembl:ENSMUSG00000041809 Vega:OTTMUSG00000029838
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mRib72-1; myoclonin1; 1700029F22Rik
    Orthologs
    Location:
    1; 1 A4
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (20951550..20990841)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (20941707..20980922)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6720483E21 gene Neighboring gene progestin and adipoQ receptor family member VIII Neighboring gene translocating chain-associating membrane protein 2 Neighboring gene transmembrane protein 14A Neighboring gene predicted gene, 32947

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein C-terminus binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cellular calcium ion homeostasis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    cerebral cortex cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    axoneme IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    EF-hand domain-containing protein 1
    Names
    myoclonin-1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027974.1NP_082250.1  EF-hand domain-containing protein 1

      See identical proteins and their annotated locations for NP_082250.1

      Status: VALIDATED

      Source sequence(s)
      AC156980, AK006489, BY037196, EU520262
      Consensus CDS
      CCDS48227.1
      UniProtKB/Swiss-Prot
      Q9D9T8
      UniProtKB/TrEMBL
      B2CKC6
      Related
      ENSMUSP00000042343.4, OTTMUSP00000038413, ENSMUST00000038447.5, OTTMUST00000074047
      Conserved Domains (4) summary
      smart00676
      Location:416520
      DM10; Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases
      cd00051
      Location:587647
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam06565
      Location:122153
      DUF1126; Repeat of unknown function (DUF1126)
      pfam13499
      Location:587646
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      20951550..20990841
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006495576.3XP_006495639.1  EF-hand domain-containing protein 1 isoform X1

      Conserved Domains (2) summary
      smart00676
      Location:93198
      DM10; Domains in hypothetical proteins in Drosophila, C. elegans and mammals. Occurs singly in some nucleoside diphosphate kinases
      pfam06565
      Location:122153
      DUF1126; Repeat of unknown function (DUF1126)
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