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    Akt1 AKT serine/threonine kinase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24185, updated on 15-May-2017
    Official Symbol
    Akt1provided by RGD
    Official Full Name
    AKT serine/threonine kinase 1provided by RGD
    Primary source
    RGD:2081
    See related
    Ensembl:ENSRNOG00000028629
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Akt
    Summary
    inhibits JUN kinase activation and mediates inhibition of apoptosis [RGD, Feb 2006]
    Orthologs
    Location:
    6q32
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (137218398..137239970, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 6 NC_005105.3 (146225955..146247008, complement)

    Chromosome 6 - NC_005105.4Genomic Context describing neighboring genes Neighboring gene adenylosuccinate synthase like 1 Neighboring gene SIVA1, apoptosis-inducing factor Neighboring gene zinc finger and BTB domain containing 42 Neighboring gene centrosomal protein 170B Neighboring gene uncharacterized LOC102552635 Neighboring gene phospholipase D family, member 4

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    14-3-3 protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    14-3-3 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTPase activating protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enzyme binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    nitric-oxide synthase regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    nitric-oxide synthase regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol-3,4,5-trisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylinositol-3,4-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol-3,4-bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase C binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphatase 2A binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein serine/threonine kinase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    protein serine/threonine/tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine/tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    I-kappaB kinase/NF-kappaB signaling IEA
    Inferred from Electronic Annotation
    more info
     
    I-kappaB kinase/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    NIK/NF-kappaB signaling IEA
    Inferred from Electronic Annotation
    more info
     
    NIK/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    activation-induced cell death of T cells IEA
    Inferred from Electronic Annotation
    more info
     
    activation-induced cell death of T cells ISO
    Inferred from Sequence Orthology
    more info
     
    aging IDA
    Inferred from Direct Assay
    more info
    PubMed 
    apoptotic mitochondrial changes IEA
    Inferred from Electronic Annotation
    more info
     
    apoptotic mitochondrial changes ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to DNA damage stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to cadmium ion IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to cadmium ion ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to decreased oxygen levels ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to epidermal growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to epidermal growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to granulocyte macrophage colony-stimulating factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to granulocyte macrophage colony-stimulating factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to hypoxia IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to insulin stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to insulin stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to mechanical stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to nerve growth factor stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to nerve growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to organic cyclic compound IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to peptide ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to prostaglandin E stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to prostaglandin E stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to reactive oxygen species IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to reactive oxygen species ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to vascular endothelial growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to vascular endothelial growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of protein localization to mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    establishment of protein localization to mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    execution phase of apoptosis IEA
    Inferred from Electronic Annotation
    more info
     
    execution phase of apoptosis ISO
    Inferred from Sequence Orthology
    more info
     
    germ cell development IEA
    Inferred from Electronic Annotation
    more info
     
    germ cell development ISO
    Inferred from Sequence Orthology
    more info
     
    glucose homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    glucose homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    glucose metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    glucose transport IEA
    Inferred from Electronic Annotation
    more info
     
    glucose transport ISO
    Inferred from Sequence Orthology
    more info
     
    glycogen biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glycogen cell differentiation involved in embryonic placenta development IEA
    Inferred from Electronic Annotation
    more info
     
    glycogen cell differentiation involved in embryonic placenta development ISO
    Inferred from Sequence Orthology
    more info
     
    glycogen metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    hyaluronan metabolic process IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    inflammatory response ISO
    Inferred from Sequence Orthology
    more info
     
    insulin receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    insulin receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    insulin receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    insulin-like growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    insulin-like growth factor receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    interleukin-18-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    interleukin-18-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    labyrinthine layer blood vessel development IEA
    Inferred from Electronic Annotation
    more info
     
    labyrinthine layer blood vessel development ISO
    Inferred from Sequence Orthology
    more info
     
    lipopolysaccharide-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    lipopolysaccharide-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    maintenance of protein location in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    maintenance of protein location in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    maternal placenta development IEA
    Inferred from Electronic Annotation
    more info
     
    maternal placenta development ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of JNK cascade IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of apoptotic process TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell size IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of endopeptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of fatty acid beta-oxidation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of fatty acid beta-oxidation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene expression IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of plasma membrane long-chain fatty acid transport IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of plasma membrane long-chain fatty acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of protein kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of proteolysis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of release of cytochrome c from mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of release of cytochrome c from mitochondria ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    osteoblast differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    osteoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    peptidyl-serine phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    peptidyl-threonine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    peripheral nervous system myelin maintenance IEA
    Inferred from Electronic Annotation
    more info
     
    peripheral nervous system myelin maintenance ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylinositol 3-kinase signaling IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol 3-kinase signaling ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylinositol-mediated signaling TAS
    Traceable Author Statement
    more info
     
    phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    platelet activation TAS
    Traceable Author Statement
    more info
     
    positive regulation of I-kappaB phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of I-kappaB phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of blood vessel endothelial cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of blood vessel endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell growth IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cellular protein metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of endodeoxyribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of endodeoxyribonuclease activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of endothelial cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of establishment of protein localization to plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of establishment of protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of fat cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of fibroblast migration IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of fibroblast migration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of glucose import IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of glucose import ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of glucose metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of glycogen biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of glycogen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of lipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of lipid biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of nitric oxide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of nitric oxide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of nitric-oxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of nitric-oxide synthase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of organ growth IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of organ growth ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein localization to nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein localization to nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of sequence-specific DNA binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of sequence-specific DNA binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of smooth muscle cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of smooth muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of sodium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of sodium ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of vasoconstriction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    protein import into nucleus, translocation IEA
    Inferred from Electronic Annotation
    more info
     
    protein import into nucleus, translocation ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase B signaling IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase B signaling ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of glycogen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of myelination IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of myelination ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    response to UV-A IEA
    Inferred from Electronic Annotation
    more info
     
    response to UV-A ISO
    Inferred from Sequence Orthology
    more info
     
    response to fluid shear stress IEA
    Inferred from Electronic Annotation
    more info
     
    response to fluid shear stress ISO
    Inferred from Sequence Orthology
    more info
     
    response to food IEA
    Inferred from Electronic Annotation
    more info
     
    response to food ISO
    Inferred from Sequence Orthology
    more info
     
    response to growth hormone ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to hormone ISO
    Inferred from Sequence Orthology
    more info
     
    response to insulin-like growth factor stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to organic substance ISO
    Inferred from Sequence Orthology
    more info
     
    response to oxidative stress ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spinal cord development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    striated muscle cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    striated muscle cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    translation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary basal body IEA
    Inferred from Electronic Annotation
    more info
     
    ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol TAS
    Traceable Author Statement
    more info
     
    microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm TAS
    Traceable Author Statement
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein complex IEA
    Inferred from Electronic Annotation
    more info
     
    spindle IEA
    Inferred from Electronic Annotation
    more info
     
    spindle ISO
    Inferred from Sequence Orthology
    more info
     
    vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    RAC-alpha serine/threonine-protein kinase
    Names
    AKT1 kinase
    PKB alpha
    RAC protein kinase alpha RAC-PK alpha
    RAC-PK-alpha
    murine thymoma viral (v-akt) oncogene homolog 1
    protein kinase B alpha
    thymoma viral proto-oncogene 1
    v-akt murine thymoma viral oncogene homolog 1
    NP_150233.1
    XP_006240693.1
    XP_008763140.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033230.2NP_150233.1  RAC-alpha serine/threonine-protein kinase

      See identical proteins and their annotated locations for NP_150233.1

      Status: PROVISIONAL

      Source sequence(s)
      D30040
      UniProtKB/Swiss-Prot
      P47196
      Related
      ENSRNOP00000038369.2, ENSRNOT00000031164.3
      Conserved Domains (4) summary
      cd01241
      Location:4111
      PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
      cd05594
      Location:124479
      STKc_PKB_alpha; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B alpha (also called Akt1)
      pfam00069
      Location:150408
      Pkinase; Protein kinase domain
      pfam00169
      Location:6104
      PH; PH domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005105.4 Reference Rnor_6.0 Primary Assembly

      Range
      137218398..137239970 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006240631.2XP_006240693.1  RAC-alpha serine/threonine-protein kinase isoform X1

      See identical proteins and their annotated locations for XP_006240693.1

      UniProtKB/Swiss-Prot
      P47196
      Conserved Domains (4) summary
      cd01241
      Location:4111
      PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
      cd05594
      Location:124479
      STKc_PKB_alpha; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B alpha (also called Akt1)
      pfam00069
      Location:150408
      Pkinase; Protein kinase domain
      pfam00169
      Location:6104
      PH; PH domain
    2. XM_008764918.2XP_008763140.1  RAC-alpha serine/threonine-protein kinase isoform X2

      Conserved Domains (4) summary
      cd01241
      Location:4111
      PH_PKB; Protein Kinase B-like pleckstrin homology (PH) domain
      cd05571
      Location:154466
      STKc_PKB; Catalytic domain of the Serine/Threonine Kinase, Protein Kinase B
      pfam00069
      Location:150408
      Pkinase; Protein kinase domain
      pfam00169
      Location:6104
      PH; PH domain

    Alternate Rn_Celera

    Genomic

    1. AC_000074.1 Alternate Rn_Celera

      Range
      129262032..129279096 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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