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    ARG82 inositol polyphosphate multikinase [ Saccharomyces cerevisiae S288c ]

    Gene ID: 851753, updated on 25-May-2017
    Gene symbol
    ARG82
    Gene description
    inositol polyphosphate multikinase
    Primary source
    SGD:S000002580
    Locus tag
    YDR173C
    Gene type
    protein coding
    RNA name
    inositol polyphosphate multikinase
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ARGR3; IPK2
    See ARG82 in Map Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (810565..811632, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene heat shock protein HSP42 Neighboring gene translation termination factor GTPase eRF3 Neighboring gene Hmo1p Neighboring gene mitochondrial 37S ribosomal protein RSM24

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    inositol tetrakisphosphate 3-kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    inositol tetrakisphosphate 6-kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    inositol-1,3,4,5,6-pentakisphosphate kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    inositol-1,4,5-trisphosphate 3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    inositol-1,4,5-trisphosphate 3-kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    inositol-1,4,5-trisphosphate 6-kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    inositol-1,4,5-trisphosphate 6-kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol 3-kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding, bridging IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein binding, bridging IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    arginine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    inositol phosphate biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    macroautophagy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphatidylinositol phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of arginine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    inositol polyphosphate multikinase
    NP_010458.3
    • Inositol polyphosphate multikinase (IPMK); sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      810565..811632 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180480.3NP_010458.3  TPA: inositol polyphosphate multikinase [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_010458.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P07250
      Conserved Domains (1) summary
      pfam03770
      Location:114352
      IPK; Inositol polyphosphate kinase
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