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    DISC1 disrupted in schizophrenia 1 [ Homo sapiens (human) ]

    Gene ID: 27185, updated on 22-Jun-2017
    Official Symbol
    DISC1provided by HGNC
    Official Full Name
    disrupted in schizophrenia 1provided by HGNC
    Primary source
    HGNC:HGNC:2888
    See related
    Ensembl:ENSG00000162946 MIM:605210; Vega:OTTHUMG00000037835
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    SCZD9; C1orf136
    Summary
    This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
    Orthologs
    Location:
    1q42.2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 1 NC_000001.11 (231626815..232041272)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (231762561..232177018)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene TSNAX-DISC1 readthrough (NMD candidate) Neighboring gene translin associated factor X Neighboring gene long intergenic non-protein coding RNA 582 Neighboring gene RNA, U5A small nuclear 5, pseudogene Neighboring gene uncharacterized LOC105373170 Neighboring gene disrupted in schizophrenia 2 (non-protein coding) Neighboring gene DISC1 intronic transcript 1 Neighboring gene uncharacterized LOC105373172 Neighboring gene uncharacterized LOC105373171

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Associated conditions

    Description Tests
    Schizophrenia
    MedGen: C0036341 OMIM: 181500 GeneReviews: Not available
    Compare labs
    Schizophrenia 9
    MedGen: C1858050 OMIM: 604906 GeneReviews: Not available
    Compare labs

    Copy number response

    Description
    Copy number response
    Haploinsufficency

    No evidence available (Last evaluated (2012-03-06)

    ClinGen Genome Curation Page
    Triplosensitivity

    No evidence available (Last evaluated (2012-03-06)

    ClinGen Genome Curation Page

    NHGRI GWAS Catalog

    Description
    Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial.
    NHGRI GWA Catalog
    Genome-wide association of lipid-lowering response to statins in combined study populations.
    NHGRI GWA Catalog
    Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.
    NHGRI GWA Catalog
    Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes.
    NHGRI GWA Catalog
    Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis.
    NHGRI GWA Catalog
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Readthrough TSNAX-DISC1

    Readthrough gene: TSNAX-DISC1, Included gene: TSNAX

    Homology

    Clone Names

    • FLJ13381, FLJ21640, FLJ25311, FLJ41105, KIAA0457

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    kinesin binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex scaffold activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    TOR signaling IEA
    Inferred from Electronic Annotation
    more info
     
    canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    cell proliferation in forebrain IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrial calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    non-motile cilium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of Wnt signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of axon extension IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of neuroblast proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    protein localization to centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    pyramidal neuron migration IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of dendritic spine development IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of synapse maturation IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
     
    response to electrical stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    axon IEA
    Inferred from Electronic Annotation
    more info
     
    cell body IEA
    Inferred from Electronic Annotation
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    central region of growth cone IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ciliary basal body IEA
    Inferred from Electronic Annotation
    more info
     
    ciliary base IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    dynein complex IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    kinesin complex IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic density of dendrite IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    disrupted in schizophrenia 1 protein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_011681.1 RefSeqGene

      Range
      5001..419458
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001012957.1NP_001012975.1  disrupted in schizophrenia 1 protein isoform Lv

      See identical proteins and their annotated locations for NP_001012975.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (Lv) has an alternate splice site in the 3' coding region, as compared to variant L. The reading frame is not changed, and the resulting isoform (Lv, also known as the "Long variant" isoform) lacks an internal segment, as compared to isoform L.
      Source sequence(s)
      AB007926, AI075754, AJ506177, AJ506178
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000355597.5, OTTHUMP00000035956, ENST00000366637.7, OTTHUMT00000092352
      Conserved Domains (1) summary
      COG1196
      Location:458798
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    2. NM_001012958.1NP_001012976.1  disrupted in schizophrenia 1 protein isoform Es

      See identical proteins and their annotated locations for NP_001012976.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (Es) lacks multiple 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (Es, also known as the "Extremely short" isoform) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      AJ506178
      Consensus CDS
      CCDS31056.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000320784.4, OTTHUMP00000035959, ENST00000317586.8, OTTHUMT00000092355
    3. NM_001012959.1NP_001012977.1  disrupted in schizophrenia 1 protein isoform S

      See identical proteins and their annotated locations for NP_001012977.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (S) lacks several 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (S, also known as the "Short" isoform) is shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      AJ506177, AJ506178, BC038954
      Consensus CDS
      CCDS31055.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000355596.4, OTTHUMP00000035960, ENST00000366636.8, OTTHUMT00000092356
      Conserved Domains (1) summary
      COG1196
      Location:337659
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    4. NM_001164537.1NP_001158009.1  disrupted in schizophrenia 1 protein isoform a

      See identical proteins and their annotated locations for NP_001158009.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (a) has an additional exon in the 5' coding region, as compared to variant L. The reading frame is not changed, but the resulting isoform (a, also known as isoform 8) is longer than isoform L.
      Source sequence(s)
      AL450284, FJ804179
      UniProtKB/TrEMBL
      C4P096
      Conserved Domains (1) summary
      cl12013
      Location:621743
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    5. NM_001164538.1NP_001158010.1  disrupted in schizophrenia 1 protein isoform b

      See identical proteins and their annotated locations for NP_001158010.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (b) lacks two 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (b, also known as isoform 10) is shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      BC142622, FJ804181
      UniProtKB/TrEMBL
      C4P098
      Conserved Domains (1) summary
      cl12013
      Location:589711
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    6. NM_001164539.1NP_001158011.1  disrupted in schizophrenia 1 protein isoform c

      See identical proteins and their annotated locations for NP_001158011.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (c) lacks several 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (c, also known as isoform 26) is shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804196
      Consensus CDS
      CCDS53482.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000355593.3, OTTHUMP00000272060, ENST00000366633.7, OTTHUMT00000467434
      Conserved Domains (1) summary
      pfam13900
      Location:677713
      GVQW; Putative domain of unknown function
    7. NM_001164540.1NP_001158012.1  disrupted in schizophrenia 1 protein isoform d

      See identical proteins and their annotated locations for NP_001158012.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (d) lacks two internal exons in the 5' region, as compared to variant L. The reading frame is not changed, and the resulting isoform (d, also kown as isoform 6) lacks an internal segment, as compared to isoform L.
      Source sequence(s)
      FJ804177
      UniProtKB/TrEMBL
      C4P094
      Related
      ENSP00000482174.1, ENST00000620189.3
      Conserved Domains (1) summary
      cl12013
      Location:467589
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    8. NM_001164541.1NP_001158013.1  disrupted in schizophrenia 1 protein isoform e

      See identical proteins and their annotated locations for NP_001158013.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (e) lacks an internal exon and two end exons in the 3' region, but has an alternate 3' segment, as compared to variant L. The resulting isoform (e, also known as isoform 15) lacks an internal segment, and has a distinct and shorter C-terminus, as compared to isoform L.
      Source sequence(s)
      BC142622, FJ804186
      Consensus CDS
      CCDS53483.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000443996.1, OTTHUMP00000279310, ENST00000535983.5, OTTHUMT00000484321
      Conserved Domains (1) summary
      COG1196
      Location:337659
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    9. NM_001164542.1NP_001158014.1  disrupted in schizophrenia 1 protein isoform f

      See identical proteins and their annotated locations for NP_001158014.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (f) lacks several 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (f, also known as isoform 16) is C-terminal truncated, as compared to isoform L.
      Source sequence(s)
      FJ804187
      UniProtKB/TrEMBL
      C4P0A4
      Conserved Domains (1) summary
      COG1196
      Location:337678
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    10. NM_001164544.1NP_001158016.1  disrupted in schizophrenia 1 protein isoform g

      See identical proteins and their annotated locations for NP_001158016.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (g) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (g, also known as isoform 29) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804199
      Consensus CDS
      CCDS59205.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000473425.1, OTTHUMP00000272074, ENST00000602281.5, OTTHUMT00000467451
      Conserved Domains (1) summary
      COG1196
      Location:337659
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    11. NM_001164545.1NP_001158017.1  disrupted in schizophrenia 1 protein isoform h

      See identical proteins and their annotated locations for NP_001158017.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (h) lacks an internal exon and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (h, also known as isoform 35) is much shorter and has a distict C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804205
      Consensus CDS
      CCDS53484.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000440953.1, OTTHUMP00000272072, ENST00000539444.5, OTTHUMT00000467449
      Conserved Domains (1) summary
      COG1196
      Location:346571
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    12. NM_001164546.1NP_001158018.1  disrupted in schizophrenia 1 protein isoform i

      See identical proteins and their annotated locations for NP_001158018.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (i) lacks three internal exons and three 3' exons but has an alternate 3' segment, as compared to variant L. Variants i and j encode the same isoform (i), which is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804190
      Consensus CDS
      CCDS53485.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000487190.1, OTTHUMP00000279309, ENST00000628350.2, OTTHUMT00000484320
      Conserved Domains (1) summary
      pfam14988
      Location:341488
      DUF4515; Domain of unknown function (DUF4515)
    13. NM_001164547.1NP_001158019.1  disrupted in schizophrenia 1 protein isoform i

      See identical proteins and their annotated locations for NP_001158019.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (j) lacks three internal exons and two 3' exons but has an alternate 3' segment, as compared to variant L. Variants i and j encode the same isoform (i), which is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      BC142622, FJ804184
      Consensus CDS
      CCDS53485.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Conserved Domains (1) summary
      pfam14988
      Location:341488
      DUF4515; Domain of unknown function (DUF4515)
    14. NM_001164548.1NP_001158020.1  disrupted in schizophrenia 1 protein isoform k

      See identical proteins and their annotated locations for NP_001158020.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (k) lacks two internal exons and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (k, also known as isoform 32) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804202
      UniProtKB/TrEMBL
      C4P0A5
      Related
      ENSP00000295051.7, OTTHUMP00000272073, ENST00000295051.11, OTTHUMT00000467450
      Conserved Domains (1) summary
      pfam14988
      Location:341488
      DUF4515; Domain of unknown function (DUF4515)
    15. NM_001164549.1NP_001158021.1  disrupted in schizophrenia 1 protein isoform l

      See identical proteins and their annotated locations for NP_001158021.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (l) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (l, also known as isoform 37) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804207
      UniProtKB/TrEMBL
      C4P0C4
      Conserved Domains (1) summary
      pfam14988
      Location:341488
      DUF4515; Domain of unknown function (DUF4515)
    16. NM_001164550.1NP_001158022.1  disrupted in schizophrenia 1 protein isoform m

      See identical proteins and their annotated locations for NP_001158022.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (m) lacks multiple 3' exons but has two alternate 3' exons, as compared to variant L. The resulting isoform (m, also known as isoform 45) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804215
      UniProtKB/TrEMBL
      C4P0D2
    17. NM_001164551.1NP_001158023.1  disrupted in schizophrenia 1 protein isoform n

      See identical proteins and their annotated locations for NP_001158023.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (n) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (n, also known as isoform 41) is much shorter and has a truncated C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804211
      UniProtKB/TrEMBL
      C4P0C8
      Related
      ENSP00000481791.1, ENST00000622252.4
    18. NM_001164552.1NP_001158024.1  disrupted in schizophrenia 1 protein isoform o

      See identical proteins and their annotated locations for NP_001158024.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (o) lacks multiple 3' exons but has two alternate 3' exons, as compared to variant L. The resulting isoform (o, also known as isoform 44) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804214
      UniProtKB/TrEMBL
      C4P0D1
    19. NM_001164553.1NP_001158025.1  disrupted in schizophrenia 1 protein isoform p

      See identical proteins and their annotated locations for NP_001158025.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (p) lacks multiple 3' exons but has an alternate 3' exon, as compared to variant L. The resulting isoform (p, also known as isoform 43) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804213
      UniProtKB/TrEMBL
      C4P0D0
    20. NM_001164554.1NP_001158026.1  disrupted in schizophrenia 1 protein isoform q

      See identical proteins and their annotated locations for NP_001158026.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (q) lacks multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (q, also known as isoform 46) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804216
      UniProtKB/TrEMBL
      C4P0D3
      Related
      ENSP00000355592.2, OTTHUMP00000272061, ENST00000366632.6, OTTHUMT00000467435
    21. NM_001164555.1NP_001158027.1  disrupted in schizophrenia 1 protein isoform r

      See identical proteins and their annotated locations for NP_001158027.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (r) lacks an internal exon and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (r, also known as isoform 42) is much shorter and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804212
      Consensus CDS
      CCDS59206.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000491762.1, OTTHUMP00000272069, ENST00000639374.1, OTTHUMT00000467446
    22. NM_001164556.1NP_001158028.1  disrupted in schizophrenia 1 protein isoform t

      See identical proteins and their annotated locations for NP_001158028.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (t) lacks four internal exons and multiple 3' exons but has an alternate 3' segment, as compared to variant L. The resulting isoform (t, also known as isoform 34) is the shortest, and has a distinct C-terminus, as compared to isoform L.
      Source sequence(s)
      FJ804204
      Consensus CDS
      CCDS59207.1
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000473386.1, OTTHUMP00000272068, ENST00000602873.5, OTTHUMT00000467445
    23. NM_018662.2NP_061132.2  disrupted in schizophrenia 1 protein isoform L

      See identical proteins and their annotated locations for NP_061132.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (L) encodes isoform L, also known as the "Long" isoform.
      Source sequence(s)
      AB007926, AF222980, AI075754, AJ506178
      UniProtKB/Swiss-Prot
      Q9NRI5
      Related
      ENSP00000403888.2, OTTHUMP00000035955, ENST00000439617.6, OTTHUMT00000092351
      Conserved Domains (2) summary
      COG1196
      Location:337678
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02169
      Location:527842
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p7 Primary Assembly

      Range
      231626815..232041272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018912.2 Alternate CHM1_1.1

      Range
      233036406..233450761
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001039383.1: Suppressed sequence

      Description
      NM_001039383.1: This RefSeq was permanently suppressed because the transcript is intronless, has sequence similarity repetitive sequence, and the protein is not supported by homology.
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