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    GP spike glycoprotein [ Zaire ebolavirus ]

    Gene ID: 911829, updated on 6-Sep-2017
    Gene symbol
    GP
    Gene description
    spike glycoprotein
    Locus tag
    ZEBOVgp4
    Gene type
    protein coding
    RNA name
    sGP
    RefSeq status
    PROVISIONAL
    Organism
    Zaire ebolavirus (isolate: Ebola virus/H.sapiens-tc/COD/1976/Yambuku-Mayinga)
    Lineage
    Viruses; ssRNA viruses; ssRNA negative-strand viruses; Mononegavirales; Filoviridae; Ebolavirus
    Sequence:
    NC_002549.1 (5900..8305)

    NC_002549.1Genomic Context describing neighboring genes Neighboring gene nucleoprotein Neighboring gene polymerase complex protein Neighboring gene coalesce nucleocapsids and cell membranes in virion assembly (budding) Neighboring gene minor nucleoprotein Neighboring gene membrane-associated protein Neighboring gene RNA-dependent RNA polymerase

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    regulatory

    • Loc: 5900-5911 regulatory_class = other
    • Loc: 6918-6924 function = RNA editing , regulatory_class = other
    • Loc: 8288-8299 regulatory_class = other
    • Loc: 8295-8305 regulatory_class = polyA_signal_sequence
    Names
    spike glycoprotein
    small secreted glycoprotein
    second secreted glycoprotein
    NP_066246.1
    • virion spike glycoprotein precursor; an additional A residue is inserted during transcription; encodes two disulfide linked subunits GP1 and GP2
    NP_066247.1
    • sGP, small non-structural, secreted glycoprotein; sGP secreted as an anti-parallel oriented homodimer
    NP_066248.1
    • second non-structural secreted glycoprotein; super small secreted glycoprotein; secreted in a monomeric form; one A residue is deleted or two additional A residues are inserted at the editing site during transcription of the GP gene

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002549.1 Reference assembly

      Range
      5900..8305
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_066246.1 spike glycoprotein [Zaire ebolavirus]

      See identical proteins and their annotated locations for NP_066246.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q05320
      UniProtKB/TrEMBL
      A0A089X075, A9QPL9
      Conserved Domains (3) summary
      cd09850
      Location:557629
      Ebola-like_HR1-HR2; heptad repeat 1-heptad repeat 2 region of the transmembrane subunit of Filoviridae viruses, Ebola virus and Marburg virus, and related domains
      pfam01611
      Location:15348
      Filo_glycop; Filovirus glycoprotein
      cl28464
      Location:341493
      Spr; Cell wall-associated hydrolase, NlpC family [Cell wall/membrane/envelope biogenesis]
    2. NP_066247.1 small secreted glycoprotein [Zaire ebolavirus]

      See identical proteins and their annotated locations for NP_066247.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P60170, P60171
      UniProtKB/TrEMBL
      A0A089YMW7, A9QPM0
      Conserved Domains (1) summary
      pfam01611
      Location:15298
      Filo_glycop; Filovirus glycoprotein
    3. NP_066248.1 second secreted glycoprotein [Zaire ebolavirus]

      See identical proteins and their annotated locations for NP_066248.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9YMG2
      UniProtKB/TrEMBL
      L7QHW1
      Conserved Domains (1) summary
      pfam01611
      Location:15295
      Filo_glycop; Filovirus glycoprotein
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