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    TEP1 putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855595, updated on 7-May-2017
    Gene symbol
    TEP1
    Gene description
    putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
    Primary source
    SGD:S000005072
    Locus tag
    YNL128W
    Gene type
    protein coding
    RNA name
    putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    See TEP1 in Map Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (382359..383663)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Dgr1p Neighboring gene ribosylnicotinamide kinase Neighboring gene Far11p Neighboring gene Spc98p

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein tyrosine/serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    peptidyl-tyrosine dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    NOT phosphatidylinositol dephosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    NOT phosphatidylinositol dephosphorylation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
    NP_014271.3
    • PTEN homolog with no demonstrated inositol lipid phosphatase activity; plays a role in normal sporulation; homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 and fission yeast ptn1

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      382359..383663
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182966.4NP_014271.3  TPA: putative phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_014271.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P53916
      Conserved Domains (2) summary
      COG2453
      Location:79265
      CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]
      cl21483
      Location:170229
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
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