Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    TOS3 serine/threonine protein kinase TOS3 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 852696, updated on 7-May-2017
    Gene symbol
    TOS3
    Gene description
    serine/threonine protein kinase TOS3
    Primary source
    SGD:S000003147
    Locus tag
    YGL179C
    Gene type
    protein coding
    RNA name
    serine/threonine protein kinase TOS3
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    See TOS3 in Map Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (163409..165091, complement)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Gts1p Neighboring gene serine/threonine protein kinase ATG1 Neighboring gene Mpt5p Neighboring gene hypothetical protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    glucose metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    glucose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    peptidyl-threonine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cell division site IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    serine/threonine protein kinase TOS3
    NP_011336.3
    • Protein kinase; related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome; TOS3 has a paralog, SAK1, that arose from the whole genome duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      163409..165091 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181044.3NP_011336.3  TPA: serine/threonine protein kinase TOS3 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_011336.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P43637
      Conserved Domains (2) summary
      smart00220
      Location:50344
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14008
      Location:56344
      STKc_LKB1_CaMKK; Catalytic domain of the Serine/Threonine kinases, Liver Kinase B1, Calmodulin Dependent Protein Kinase Kinase, and similar proteins
    Support Center