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    CLS cardiolipin synthase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825825, updated on 28-Mar-2017
    Gene symbol
    CLS
    Gene description
    cardiolipin synthase
    Primary source
    Araport:AT4G04870
    Locus tag
    AT4G04870
    Gene type
    protein coding
    RNA name
    cardiolipin synthase
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cardiolipin synthase; T4B21.19; T4B21_19
    Summary
    Encodes a protein with cardiolipin synthase activity that is localized to the mitochondiria.
    See CLS in Map Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (2461674..2464150, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene K+ efflux antiporter 3 Neighboring gene ncRNA Neighboring gene DERLIN-2.2 Neighboring gene adenosine/AMP deaminase family protein Neighboring gene PCF11P-similar protein 4

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NM_116725.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    cardiolipin synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    manganese ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phosphatidyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    cardiolipin biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    phospholipid biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISM
    Inferred from Sequence Model
    more info
     
    Names
    cardiolipin synthase
    NP_567273.1
    • cardiolipin synthase (CLS); FUNCTIONS IN: phosphatidyltransferase activity, cardiolipin synthase activity; INVOLVED IN: phospholipid biosynthetic process; LOCATED IN: mitochondrion; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CDP-alcohol phosphatidyltransferase (InterPro:IPR000462); BEST Arabidopsis thaliana protein match is: phosphatidylglycerolphosphate synthase 2 (TAIR:AT3G55030.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      2461674..2464150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116725.5NP_567273.1  cardiolipin synthase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567273.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93YW7
      Conserved Domains (2) summary
      PLN02794
      Location:1341
      PLN02794; cardiolipin synthase
      COG0558
      Location:143332
      PgsA; Phosphatidylglycerophosphate synthase [Lipid transport and metabolism]
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