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    Fcgrt Fc fragment of IgG receptor and transporter [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29558, updated on 2-Jul-2017
    Official Symbol
    Fcgrtprovided by RGD
    Official Full Name
    Fc fragment of IgG receptor and transporterprovided by RGD
    Primary source
    RGD:61811
    See related
    Ensembl:ENSRNOG00000020583
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    FcRn
    Summary
    binds and transports maternal immunoglobulin gamma from milk; plays a role in providing maternal immunity to neonates [RGD, Feb 2006]
    Orthologs
    Location:
    1q22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (101086872..101096159, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (102151852..102161703, complement)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene proline rich and Gla domain 2 Neighboring gene nitric oxide synthase interacting protein Neighboring gene reticulocalbin 3 Neighboring gene microRNA 150 Neighboring gene ribosomal protein S11

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    IgG binding IEA
    Inferred from Electronic Annotation
    more info
     
    IgG binding ISO
    Inferred from Sequence Orthology
    more info
     
    IgG receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    beta-2-microglobulin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT peptide antigen binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    Fc-gamma receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    humoral immune response TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    IgG receptor FcRn large subunit p51
    Names
    Fc fragment immunoglobulin G receptor
    Fc fragment of IgG, receptor, transporter, alpha
    Fc receptor, IgG, alpha chain transporter
    igG Fc fragment receptor transporter alpha chain
    neonatal Fc receptor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033351.2NP_203502.1  IgG receptor FcRn large subunit p51 precursor

      See identical proteins and their annotated locations for NP_203502.1

      Status: PROVISIONAL

      Source sequence(s)
      M35495
      UniProtKB/Swiss-Prot
      P13599
      Related
      ENSRNOP00000027944.4, ENSRNOT00000027944.6
      Conserved Domains (2) summary
      pfam00129
      Location:25198
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
      cl11960
      Location:202289
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      101086872..101096159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017589060.1XP_017444549.1  IgG receptor FcRn large subunit p51 isoform X2

    2. XM_008759343.2XP_008757565.1  IgG receptor FcRn large subunit p51 isoform X1

      See identical proteins and their annotated locations for XP_008757565.1

      UniProtKB/Swiss-Prot
      P13599
      Conserved Domains (2) summary
      pfam00129
      Location:25198
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
      cl11960
      Location:202289
      Ig; Immunoglobulin domain
    3. XM_006229043.2XP_006229105.1  IgG receptor FcRn large subunit p51 isoform X1

      See identical proteins and their annotated locations for XP_006229105.1

      UniProtKB/Swiss-Prot
      P13599
      Conserved Domains (2) summary
      pfam00129
      Location:25198
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
      cl11960
      Location:202289
      Ig; Immunoglobulin domain

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      89835561..89844654 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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