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    F10 coagulation factor X [ Bos taurus (cattle) ]

    Gene ID: 280787, updated on 12-Mar-2017
    Gene symbol
    F10
    Gene description
    coagulation factor X
    See related
    BGD:BT23406; Ensembl:ENSBTAG00000016385
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    Location:
    chromosome: 12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    105 current Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 12 AC_000169.1 (90516721..90530178)

    Chromosome 12 - AC_000169.1Genomic Context describing neighboring genes Neighboring gene MCF.2 cell line derived transforming sequence like Neighboring gene uncharacterized LOC101902449 Neighboring gene coagulation factor VII Neighboring gene protein Z, vitamin K dependent plasma glycoprotein Neighboring gene PCI domain containing 2

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    blood coagulation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein kinase B signaling IEA
    Inferred from Electronic Annotation
    more info
     
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    coagulation factor X
    Names
    stuart factor
    NP_001073682.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080213.1NP_001073682.1  coagulation factor X precursor

      See identical proteins and their annotated locations for NP_001073682.1

      Status: VALIDATED

      Source sequence(s)
      AC150564
      UniProtKB/Swiss-Prot
      P00743
      Related
      ENSBTAP00000021789, ENSBTAT00000021789
      Conserved Domains (5) summary
      smart00020
      Location:233461
      Tryp_SPc; Trypsin-like serine protease
      smart00069
      Location:2285
      GLA; Domain containing Gla (gamma-carboxyglutamate) residues
      cd00054
      Location:86122
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00190
      Location:234464
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
      pfam14670
      Location:129164
      FXa_inhibition; Coagulation Factor Xa inhibitory site

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Bos_taurus_UMD_3.1.1 Primary Assembly

    Genomic

    1. AC_000169.1 Reference Bos_taurus_UMD_3.1.1 Primary Assembly

      Range
      90516721..90530178
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Btau_5.0.1

    Genomic

    1. NC_007310.6 Alternate Btau_5.0.1

      Range
      90942228..90955685
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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