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    PGM2 phosphoglucomutase PGM2 [ Saccharomyces cerevisiae S288c ]

    Gene ID: 855131, updated on 5-Mar-2017
    Gene symbol
    PGM2
    Gene description
    phosphoglucomutase PGM2
    Primary source
    SGD:S000004711
    Locus tag
    YMR105C
    Gene type
    protein coding
    RNA name
    phosphoglucomutase PGM2
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    GAL5
    See PGM2 in Map Viewer
    Location:
    chromosome: XIII
    Exon count:
    1
    Sequence:
    Chromosome: XIII; NC_001145.3 (475897..477606, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene putative protein kinase YPK2 Neighboring gene hypothetical protein Neighboring gene ATP-dependent DNA helicase YKU80

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    intramolecular transferase activity, phosphotransferases IEA
    Inferred from Electronic Annotation
    more info
     
    isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoglucomutase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoglucomutase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    phosphoglucomutase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphoglucomutase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    UDP-glucose metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    cellular calcium ion homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cellular calcium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular cation homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    galactose catabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    galactose catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glucose 1-phosphate metabolic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    glucose 1-phosphate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glucose 1-phosphate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    glucose 6-phosphate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    glucose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    glucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    glycogen biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    organic substance metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    trehalose biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Names
    phosphoglucomutase PGM2
    NP_013823.1
    • Phosphoglucomutase; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase; protein abundance increases in response to DNA replication stress; PGM2 has a paralog, PGM1, that arose from the whole genome duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      475897..477606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182605.1NP_013823.1  TPA: phosphoglucomutase PGM2 [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_013823.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P37012
      Conserved Domains (2) summary
      cd03085
      Location:6569
      PGM1; Phosphoglucomutase 1 (PGM1) catalyzes the bidirectional interconversion of glucose-1-phosphate (G-1-P) and glucose-6-phosphate (G-6-P) via a glucose 1,6-diphosphate intermediate, an important metabolic step in prokaryotes and eukaryotes. In one direction, ...
      COG0033
      Location:1555
      Pgm; Phosphoglucomutase [Carbohydrate transport and metabolism]
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