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    Ctnna1 catenin alpha 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307505, updated on 8-Oct-2017
    Official Symbol
    Ctnna1provided by RGD
    Official Full Name
    catenin alpha 1provided by RGD
    Primary source
    RGD:1359485
    See related
    Ensembl:ENSRNOG00000005796
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Catna1
    Orthologs
    Location:
    18p11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (27923229..28055972)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 18 NC_005117.3 (27633009..27766069)

    Chromosome 18 - NC_005117.4Genomic Context describing neighboring genes Neighboring gene heat shock protein family A member 9 Neighboring gene uncharacterized LOC108353164 Neighboring gene leucine rich repeat transmembrane neuronal 2 Neighboring gene SIL1 nucleotide exchange factor Neighboring gene uncharacterized LOC102550858

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC93767

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    actin filament binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    beta-catenin binding IEA
    Inferred from Electronic Annotation
    more info
     
    beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cadherin binding IEA
    Inferred from Electronic Annotation
    more info
     
    cadherin binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    gamma-catenin binding IEA
    Inferred from Electronic Annotation
    more info
     
    gamma-catenin binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    vinculin binding IEA
    Inferred from Electronic Annotation
    more info
     
    vinculin binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    actin filament organization IEA
    Inferred from Electronic Annotation
    more info
     
    aging IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    apical junction assembly IEA
    Inferred from Electronic Annotation
    more info
     
    apical junction assembly ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    axon regeneration IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular protein localization IEA
    Inferred from Electronic Annotation
    more info
     
    cellular protein localization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cellular response to indole-3-methanol IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to indole-3-methanol ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    epithelial cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    epithelial cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    establishment or maintenance of cell polarity IEA
    Inferred from Electronic Annotation
    more info
     
    establishment or maintenance of cell polarity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    gap junction assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male gonad development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of cell motility IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cell motility ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of integrin-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of neuroblast proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of neuroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    odontogenesis of dentin-containing tooth IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    ovarian follicle development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of smoothened signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of smoothened signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein heterooligomerization IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    response to estrogen IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to organic cyclic compound IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    acrosomal vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    adherens junction ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    catenin complex IEA
    Inferred from Electronic Annotation
    more info
     
    catenin complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    cell-cell adherens junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell-cell adherens junction ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cell-cell junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    flotillin complex IEA
    Inferred from Electronic Annotation
    more info
     
    flotillin complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    focal adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    intercalated disc IEA
    Inferred from Electronic Annotation
    more info
     
    intercalated disc ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    lamellipodium IEA
    Inferred from Electronic Annotation
    more info
     
    lamellipodium ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    zonula adherens IEA
    Inferred from Electronic Annotation
    more info
     
    zonula adherens ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Preferred Names
    catenin alpha-1
    Names
    catenin (cadherin associated protein), alpha 1
    catenin (cadherin-associated protein), alpha 1, 102kDa

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007145.1NP_001007146.1  catenin alpha-1

      See identical proteins and their annotated locations for NP_001007146.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085789
      UniProtKB/TrEMBL
      Q5U302
      Related
      ENSRNOP00000008041.5, ENSRNOT00000008041.7
      Conserved Domains (1) summary
      pfam01044
      Location:82869
      Vinculin; Vinculin family

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005117.4 Reference Rnor_6.0 Primary Assembly

      Range
      27923229..28055972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017600964.1XP_017456453.1  catenin alpha-1 isoform X1

      UniProtKB/TrEMBL
      Q5U302
      Conserved Domains (1) summary
      pfam01044
      Location:82869
      Vinculin; Vinculin family
    2. XM_008772037.2XP_008770259.1  catenin alpha-1 isoform X2

      See identical proteins and their annotated locations for XP_008770259.1

      Conserved Domains (1) summary
      pfam01044
      Location:1497
      Vinculin; Vinculin family
    3. XM_017600965.1XP_017456454.1  catenin alpha-1 isoform X3

    Alternate Rn_Celera

    Genomic

    1. AC_000086.1 Alternate Rn_Celera

      Range
      26463736..26596152
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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