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    Il10 interleukin 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25325, updated on 10-Dec-2017
    Official Symbol
    Il10provided by RGD
    Official Full Name
    interleukin 10provided by RGD
    Primary source
    RGD:2886
    See related
    Ensembl:ENSRNOG00000004647
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    IL10X
    Summary
    factor involved in the inhibition of cytokine synthesis [RGD, Feb 2006]
    Expression
    Biased expression in Spleen (RPKM 3.6), Thymus (RPKM 1.9) and 7 other tissues See more
    Orthologs
    Location:
    13q13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (47738933..47743392)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 13 NC_005112.3 (52824594..52828560)

    Chromosome 13 - NC_005112.4Genomic Context describing neighboring genes Neighboring gene interleukin 20 Neighboring gene interleukin 19 Neighboring gene mitogen-activated protein kinase-activated protein kinase 2 Neighboring gene uncharacterized LOC103691875 Neighboring gene dual specificity tyrosine phosphorylation regulated kinase 3

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • African trypanosomiasis, organism-specific biosystem (from KEGG)
      African trypanosomiasis, organism-specific biosystemTrypanosoma brucei, the parasite responsible for African trypanosomiasis (sleeping sickness), are spread by the tsetse fly in sub-Saharan Africa. The parasites are able to pass through the blood-brai...
    • African trypanosomiasis, conserved biosystem (from KEGG)
      African trypanosomiasis, conserved biosystemTrypanosoma brucei, the parasite responsible for African trypanosomiasis (sleeping sickness), are spread by the tsetse fly in sub-Saharan Africa. The parasites are able to pass through the blood-brai...
    • Allograft rejection, organism-specific biosystem (from KEGG)
      Allograft rejection, organism-specific biosystemAllograft rejection is the consequence of the recipient's alloimmune response to nonself antigens expressed by donor tissues. After transplantation of organ allografts, there are two pathways of anti...
    • Allograft rejection, conserved biosystem (from KEGG)
      Allograft rejection, conserved biosystemAllograft rejection is the consequence of the recipient's alloimmune response to nonself antigens expressed by donor tissues. After transplantation of organ allografts, there are two pathways of anti...
    • Amoebiasis, organism-specific biosystem (from KEGG)
      Amoebiasis, organism-specific biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...
    • Amoebiasis, conserved biosystem (from KEGG)
      Amoebiasis, conserved biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...
    • Asthma, organism-specific biosystem (from KEGG)
      Asthma, organism-specific biosystemAsthma is a complex syndrome with many clinical phenotypes in both adults and children. Its major characteristics include a variable degree of airflow obstruction, bronchial hyperresponsiveness, and ...
    • Asthma, conserved biosystem (from KEGG)
      Asthma, conserved biosystemAsthma is a complex syndrome with many clinical phenotypes in both adults and children. Its major characteristics include a variable degree of airflow obstruction, bronchial hyperresponsiveness, and ...
    • Autoimmune thyroid disease, organism-specific biosystem (from KEGG)
      Autoimmune thyroid disease, organism-specific biosystemThe classification of autoimmune throid disease (AITD) includes Hashimoto's thyroiditis (HT) or chronic autoimmune thyroiditis and its variants, Graves' disease (GD) and autoimmune atrophic thyroidi...
    • Autoimmune thyroid disease, conserved biosystem (from KEGG)
      Autoimmune thyroid disease, conserved biosystemThe classification of autoimmune throid disease (AITD) includes Hashimoto's thyroiditis (HT) or chronic autoimmune thyroiditis and its variants, Graves' disease (GD) and autoimmune atrophic thyroidi...
    • Chagas disease (American trypanosomiasis), organism-specific biosystem (from KEGG)
      Chagas disease (American trypanosomiasis), organism-specific biosystemTrypanosoma cruzi is an intracellular protozoan parasite that causes Chagas disease. The parasite life cycle involves hematophagous reduviid bugs as vectors. Once parasites enter the host body, they ...
    • Chagas disease (American trypanosomiasis), conserved biosystem (from KEGG)
      Chagas disease (American trypanosomiasis), conserved biosystemTrypanosoma cruzi is an intracellular protozoan parasite that causes Chagas disease. The parasite life cycle involves hematophagous reduviid bugs as vectors. Once parasites enter the host body, they ...
    • Cytokine Signaling in Immune system, organism-specific biosystem (from REACTOME)
      Cytokine Signaling in Immune system, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
    • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
    • Cytokines and Inflammatory Response (BioCarta), organism-specific biosystem (from WikiPathways)
      Cytokines and Inflammatory Response (BioCarta), organism-specific biosystemSee BioCarta version: http://www.biocarta.com/pathfiles/h_inflamPathway.asp
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
      Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • FoxO signaling pathway, organism-specific biosystem (from KEGG)
      FoxO signaling pathway, organism-specific biosystemThe forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellular physiological events including apoptosis, cell-cycle control, glucose metabolism, oxidative str...
    • Immune System, organism-specific biosystem (from REACTOME)
      Immune System, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Inflammatory bowel disease (IBD), organism-specific biosystem (from KEGG)
      Inflammatory bowel disease (IBD), organism-specific biosystemInflammatory bowel disease (IBD), which includes Crohn disease (CD) and ulcerative colitis (UC), is characterized by chronic inflammation of the gastrointestinal tract due to environmental and geneti...
    • Inflammatory bowel disease (IBD), conserved biosystem (from KEGG)
      Inflammatory bowel disease (IBD), conserved biosystemInflammatory bowel disease (IBD), which includes Crohn disease (CD) and ulcerative colitis (UC), is characterized by chronic inflammation of the gastrointestinal tract due to environmental and geneti...
    • Interleukin-10 signaling, organism-specific biosystem (from REACTOME)
      Interleukin-10 signaling, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Intestinal immune network for IgA production, organism-specific biosystem (from KEGG)
      Intestinal immune network for IgA production, organism-specific biosystemThe intestine is the largest lymphoid tissue in the body. One striking feature of intestinal immunity is its ability to generate great amounts of noninflammatory immunoglobulin A (IgA) antibodies tha...
    • Intestinal immune network for IgA production, conserved biosystem (from KEGG)
      Intestinal immune network for IgA production, conserved biosystemThe intestine is the largest lymphoid tissue in the body. One striking feature of intestinal immunity is its ability to generate great amounts of noninflammatory immunoglobulin A (IgA) antibodies tha...
    • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
      Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
      Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Leishmaniasis, organism-specific biosystem (from KEGG)
      Leishmaniasis, organism-specific biosystemLeishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by sandflies, where they survive and prol...
    • Leishmaniasis, conserved biosystem (from KEGG)
      Leishmaniasis, conserved biosystemLeishmania is an intracellular protozoan parasite of macrophages that causes visceral, mucosal, and cutaneous diseases. The parasite is transmitted to humans by sandflies, where they survive and prol...
    • Malaria, organism-specific biosystem (from KEGG)
      Malaria, organism-specific biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • Malaria, conserved biosystem (from KEGG)
      Malaria, conserved biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • Pertussis, organism-specific biosystem (from KEGG)
      Pertussis, organism-specific biosystemPertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory whe...
    • Pertussis, conserved biosystem (from KEGG)
      Pertussis, conserved biosystemPertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory whe...
    • Signaling by Interleukins, organism-specific biosystem (from REACTOME)
      Signaling by Interleukins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Staphylococcus aureus infection, organism-specific biosystem (from KEGG)
      Staphylococcus aureus infection, organism-specific biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...
    • Staphylococcus aureus infection, conserved biosystem (from KEGG)
      Staphylococcus aureus infection, conserved biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...
    • Systemic lupus erythematosus, organism-specific biosystem (from KEGG)
      Systemic lupus erythematosus, organism-specific biosystemSystemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the production of IgG autoantibodies that are specific for self-antigens, such as DNA, nuclear proteins and cert...
    • Systemic lupus erythematosus, conserved biosystem (from KEGG)
      Systemic lupus erythematosus, conserved biosystemSystemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterised by the production of IgG autoantibodies that are specific for self-antigens, such as DNA, nuclear proteins and cert...
    • T cell receptor signaling pathway, organism-specific biosystem (from KEGG)
      T cell receptor signaling pathway, organism-specific biosystemActivation of T lymphocytes is a key event for an efficient response of the immune system. It requires the involvement of the T-cell receptor (TCR) as well as costimulatory molecules such as CD28. En...
    • T cell receptor signaling pathway, conserved biosystem (from KEGG)
      T cell receptor signaling pathway, conserved biosystemActivation of T lymphocytes is a key event for an efficient response of the immune system. It requires the involvement of the T-cell receptor (TCR) as well as costimulatory molecules such as CD28. En...
    • Toxoplasmosis, organism-specific biosystem (from KEGG)
      Toxoplasmosis, organism-specific biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
    • Toxoplasmosis, conserved biosystem (from KEGG)
      Toxoplasmosis, conserved biosystemToxoplasma gondii is an obligate intracellular parasite that is prevalent worldwide. The tachyzoite form acquired by oral ingestion downmodulates proinflammatory signaling pathways via various mechan...
    • Tuberculosis, organism-specific biosystem (from KEGG)
      Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
    • Tuberculosis, conserved biosystem (from KEGG)
      Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    cytokine activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    interleukin-10 receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    interleukin-10 receptor binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    aging IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    branching involved in labyrinthine layer morphogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    branching involved in labyrinthine layer morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cellular response to estradiol stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to hepatocyte growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to hepatocyte growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cellular response to lipopolysaccharide IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to lipopolysaccharide ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    defense response to bacterium ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    defense response to protozoan IEA
    Inferred from Electronic Annotation
    more info
     
    defense response to protozoan ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    inflammatory response ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    inflammatory response ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    liver regeneration IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    negative regulation of B cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of B cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of chronic inflammatory response to antigenic stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of chronic inflammatory response to antigenic stimulus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cytokine activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of cytokine production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cytokine secretion involved in immune response ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of cytokine secretion involved in immune response ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of endothelial cell apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of endothelial cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    NOT negative regulation of endothelial cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of growth of symbiont in host IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of growth of symbiont in host ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of heterotypic cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of heterotypic cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of inflammatory response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of inflammatory response ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of interferon-gamma production IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of interferon-gamma production ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of interleukin-12 production IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of interleukin-12 production ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of interleukin-6 production ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of interleukin-6 production ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of membrane protein ectodomain proteolysis ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of membrane protein ectodomain proteolysis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of myeloid dendritic cell activation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of myeloid dendritic cell activation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of nitric oxide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of sensory perception of pain IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of tumor necrosis factor biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of tumor necrosis factor production ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    negative regulation of vascular smooth muscle cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of vascular smooth muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of B cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of B cell apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of DNA binding transcription factor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of DNA binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of MHC class II biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of MHC class II biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell cycle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of cytokine secretion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of cytokine secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of endothelial cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of endothelial cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of macrophage activation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    receptor biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    receptor biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    NOT regulation of complement-dependent cytotoxicity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of response to wounding IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of response to wounding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    regulation of sensory perception of pain IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of synapse organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to activity IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to carbon monoxide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to drug IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to glucocorticoid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to glucocorticoid ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    response to glucocorticoid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to inactivity IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to insulin IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to lipopolysaccharide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to molecule of bacterial origin ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    response to molecule of bacterial origin ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to organic substance IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Preferred Names
    interleukin-10
    Names
    CSIF
    IL-10
    cytokine synthesis inhibitory factor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012854.2NP_036986.2  interleukin-10 precursor

      See identical proteins and their annotated locations for NP_036986.2

      Status: PROVISIONAL

      Source sequence(s)
      L02926
      UniProtKB/Swiss-Prot
      P29456
      Related
      ENSRNOP00000006246.2, ENSRNOT00000006246.5
      Conserved Domains (1) summary
      pfam00726
      Location:33174
      IL10; Interleukin 10

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005112.4 Reference Rnor_6.0 Primary Assembly

      Range
      47738933..47743392
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006249712.3XP_006249774.1  interleukin-10 isoform X2

      Conserved Domains (1) summary
      cl02501
      Location:33149
      IL10; Interleukin 10
    2. XM_008769426.2XP_008767648.1  interleukin-10 isoform X1

      Conserved Domains (1) summary
      cl02501
      Location:33126
      IL10; Interleukin 10

    Alternate Rn_Celera

    Genomic

    1. AC_000081.1 Alternate Rn_Celera

      Range
      42821569..42825416
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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