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    Adcy10 adenylate cyclase 10 (soluble) [ Rattus norvegicus (Norway rat) ]

    Gene ID: 59320, updated on 31-Dec-2016
    Official Symbol
    Adcy10provided by RGD
    Official Full Name
    adenylate cyclase 10 (soluble)provided by RGD
    Primary source
    RGD:708450
    See related
    Ensembl:ENSRNOG00000053410
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sac
    Summary
    cytosolic adenylyl cyclase [RGD, Feb 2006]
    Orthologs
    Location:
    13q23
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (83701952..83787010)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 13 NC_005112.3 (88583534..88667840)

    Chromosome 13 - NC_005112.4Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 6 Neighboring gene mitochondrial pyruvate carrier 2 Neighboring gene myelin protein zero-like 1 Neighboring gene transfer RNA proline (anticodon AGG)

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    adenylate cyclase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    adenylate cyclase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    adenylate cyclase activity ISO
    Inferred from Sequence Orthology
    more info
     
    bicarbonate binding ISO
    Inferred from Sequence Orthology
    more info
     
    bicarbonate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    manganese ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    cAMP biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cAMP biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cAMP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to inorganic substance ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to inorganic substance ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    epithelial cilium movement ISO
    Inferred from Sequence Orthology
    more info
     
    epithelial cilium movement ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    apical part of cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    basal part of cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    growth cone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with microtubule cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with motile cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    adenylate cyclase type 10
    Names
    germ cell soluble adenylyl cyclase
    soluble adenylyl cyclase
    testicular soluble adenylyl cyclase
    NP_067716.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021684.1NP_067716.1  adenylate cyclase type 10

      See identical proteins and their annotated locations for NP_067716.1

      Status: PROVISIONAL

      Source sequence(s)
      AF081941
      UniProtKB/Swiss-Prot
      Q9Z286
      Conserved Domains (3) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
      pfam13191
      Location:485670
      AAA_16; AAA ATPase domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005112.4 Reference Rnor_6.0 Primary Assembly

      Range
      83701952..83787010
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008769677.2XP_008767899.1  

      See identical proteins and their annotated locations for XP_008767899.1

      UniProtKB/Swiss-Prot
      Q9Z286
      Conserved Domains (3) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
      pfam13191
      Location:485670
      AAA_16; AAA ATPase domain
    2. XM_008769680.2XP_008767902.1  

      Conserved Domains (3) summary
      cd07302
      Location:40235
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
      pfam13191
      Location:423608
      AAA_16; AAA ATPase domain
    3. XM_008769678.2XP_008767900.1  

      See identical proteins and their annotated locations for XP_008767900.1

      UniProtKB/Swiss-Prot
      Q9Z286
      Conserved Domains (3) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
      pfam13191
      Location:485670
      AAA_16; AAA ATPase domain
    4. XM_008769679.2XP_008767901.1  

      See identical proteins and their annotated locations for XP_008767901.1

      UniProtKB/Swiss-Prot
      Q9Z286
      Related
      ENSRNOP00000072356, ENSRNOT00000082677
      Conserved Domains (3) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
      pfam13191
      Location:485670
      AAA_16; AAA ATPase domain

    Alternate Rn_Celera

    Genomic

    1. AC_000081.1 Alternate Rn_Celera

      Range
      77464675..77547216
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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