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    Sat1 spermidine/spermine N1-acetyl transferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 20229, updated on 4-Jun-2017
    Official Symbol
    Sat1provided by MGI
    Official Full Name
    spermidine/spermine N1-acetyl transferase 1provided by MGI
    Primary source
    MGI:MGI:98233
    See related
    Ensembl:ENSMUSG00000025283 Vega:OTTMUSG00000019352
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sat; SSAT; AA617398
    Orthologs
    Location:
    X F3; X 72.38 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (155213126..155216449, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (151647681..151650952, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine decarboxylase, pseudogene 1 Neighboring gene 60S acidic ribosomal protein P0-like Neighboring gene ribosomal protein L7 pseudogene Neighboring gene acyl-CoA thioesterase 9

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    diamine N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    spermidine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    spermidine binding ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    polyamine catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    polyamine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    spermidine acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    spermidine acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    spermine catabolic process TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    diamine acetyltransferase 1
    Names
    SSAT-1
    polyamine N-acetyltransferase 1
    putrescine acetyltransferase
    spermidine/spermine N(1)-acetyltransferase 1
    NP_001278794.1
    NP_033147.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001291865.1NP_001278794.1  diamine acetyltransferase 1 isoform 2

      See identical proteins and their annotated locations for NP_001278794.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon and initiates translation at an alternate start codon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      BC058696, BU699066, BX119978, BX119986
      UniProtKB/Swiss-Prot
      P48026
      UniProtKB/TrEMBL
      Q3V2Q2
      Conserved Domains (1) summary
      pfam00583
      Location:969
      Acetyltransf_1; Acetyltransferase (GNAT) family
    2. NM_009121.4NP_033147.1  diamine acetyltransferase 1 isoform 1

      See identical proteins and their annotated locations for NP_033147.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      BC058696, BU699066, BX119986
      Consensus CDS
      CCDS30495.1
      UniProtKB/Swiss-Prot
      P48026
      Related
      ENSMUSP00000026318.8, OTTMUSP00000020874, ENSMUST00000026318.14, OTTMUST00000046198
      Conserved Domains (2) summary
      COG0456
      Location:1144
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:67144
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      155213126..155216449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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