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    Fth1 ferritin heavy polypeptide 1 [ Mus musculus (house mouse) ]

    Gene ID: 14319, updated on 3-Sep-2017
    Official Symbol
    Fth1provided by MGI
    Official Full Name
    ferritin heavy polypeptide 1provided by MGI
    Primary source
    MGI:MGI:95588
    See related
    Ensembl:ENSMUSG00000024661
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FHC; Fth; HFt; MFH
    Orthologs
    Location:
    19 A; 19 6.23 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (9980600..9985111)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (10057193..10059582)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36913 Neighboring gene predicted gene, 41806 Neighboring gene bestrophin 1 Neighboring gene RAB3A interacting protein (rabin3)-like 1

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ferric iron binding IEA
    Inferred from Electronic Annotation
    more info
     
    ferroxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    iron ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular sequestering of iron ion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    intracellular sequestering of iron ion ISO
    Inferred from Sequence Orthology
    more info
     
    iron ion import IDA
    Inferred from Direct Assay
    more info
    PubMed 
    iron ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of fibroblast proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    autolysosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    ferritin heavy chain
    Names
    H-ferritin
    ferritin H subunit
    ferritin heavy chain 1
    NP_034369.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010239.2NP_034369.1  ferritin heavy chain

      See identical proteins and their annotated locations for NP_034369.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the protein.
      Source sequence(s)
      AC134437, AK147082
      Consensus CDS
      CCDS29567.1
      UniProtKB/Swiss-Prot
      P09528
      Related
      ENSMUSP00000025563.6, ENSMUST00000025563.6
      Conserved Domains (2) summary
      cd01056
      Location:14174
      Euk_Ferritin; eukaryotic ferritins
      pfam00210
      Location:18159
      Ferritin; Ferritin-like domain

    RNA

    1. NR_073181.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an extended 5' splice structure, compared to variant 1. This variant is represented as non-coding due to the presence of an upstream ORF that is predicted to interfere with translation of the longest ORF; translation of the upstream ORF renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC134437, AK152702

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      9980600..9985111
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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