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    Slc17a8 solute carrier family 17 member 8 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 266767, updated on 25-May-2017
    Official Symbol
    Slc17a8provided by RGD
    Official Full Name
    solute carrier family 17 member 8provided by RGD
    Primary source
    RGD:628870
    See related
    Ensembl:ENSRNOG00000007581 Vega:OTTRNOG00000002178
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Vglut3
    Summary
    has glutamate transporter activity; may play a role in glutamate transport in synaptic vesicles of cholinergic and serotoninergic neurons [RGD, Feb 2006]
    Orthologs
    Location:
    7q13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (30215231..30274993, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (30314804..30371888, complement)

    Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 1, group H, member 4 Neighboring gene annexin A7-like Neighboring gene UHRF1-binding protein 1-like Neighboring gene SCY1 like pseudokinase 2 Neighboring gene ARP6 actin-related protein 6 homolog

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    L-glutamate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    L-glutamate transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    symporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    L-glutamate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    L-glutamate transport ISO
    Inferred from Sequence Orthology
    more info
     
    brain development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cochlea development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    neural retina development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    neurotransmitter transport IEA
    Inferred from Electronic Annotation
    more info
     
    sensory perception of sound IEA
    Inferred from Electronic Annotation
    more info
     
    sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    apical dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon terminus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    basilar dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    excitatory synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glial limiting end-foot IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    multivesicular body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pericellular basket IDA
    Inferred from Direct Assay
    more info
    PubMed 
    perikaryon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    vesicular glutamate transporter 3
    Names
    solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
    solute carrier family 17 (vesicular glutamate transporter), member 8

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153725.1NP_714947.1  vesicular glutamate transporter 3

      See identical proteins and their annotated locations for NP_714947.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ491795
      UniProtKB/Swiss-Prot
      Q7TSF2
      Related
      ENSRNOP00000010207.1, ENSRNOT00000010207.2
      Conserved Domains (2) summary
      cd06174
      Location:80502
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:75513
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

      Range
      30215231..30274993 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006241240.3XP_006241302.1  vesicular glutamate transporter 3 isoform X2

      Related
      ENSRNOP00000075876.1, OTTRNOP00000002106, ENSRNOT00000092527.1, OTTRNOT00000003665
      Conserved Domains (2) summary
      cd06174
      Location:100522
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:95533
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
    2. XM_008765221.2XP_008763443.1  vesicular glutamate transporter 3 isoform X1

      Conserved Domains (2) summary
      cd06174
      Location:80452
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00894
      Location:75463
      2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

    Alternate Rn_Celera

    Genomic

    1. AC_000075.1 Alternate Rn_Celera

      Range
      21139735..21191778 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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