Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    ygcB Cascade complex anti-viral R-loop helicase-annealase Cas3 [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947229, updated on 31-Jan-2018
    Gene symbol
    ygcB
    Gene description
    Cascade complex anti-viral R-loop helicase-annealase Cas3
    Primary source
    EcoGene:EG12634
    Locus tag
    b2761
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    cas3; ECK2756; JW2731
    Summary
    The Cascade antiviral complex is comprised of CasABCDE and short CRISP RNAs (crRNAs) and requires the predicted helicase YgcB(Cas3) for activity (Brouns , 2008). [More information is available at EcoGene: EG12634]. In the presence of Cas3, the Cascade complex gives rise to resistance against phages whose genomes have regions of complementarity to elements in the CRISPR repeat . [More information is available at EcoCyc: EG12634].
    Sequence:
    NC_000913.3 (2884553..2887219, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene CRISP RNA (crRNA) containing Cascade antiviral complex protein Neighboring gene CRISP RNA (crRNA) containing Cascade antiviral complex protein Neighboring gene CRISP RNA (crRNA) containing Cascade antiviral complex protein Neighboring gene ncRNA Neighboring gene phosphoadenosine phosphosulfate reductase; PAPS reductase, thioredoxin dependent

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Names
    Cascade complex anti-viral R-loop helicase-annealase Cas3

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2884553..2887219 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417241.1 Cascade complex anti-viral R-loop helicase-annealase Cas3 [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417241.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P38036
      Conserved Domains (1) summary
      PRK09694
      Location:1883
      PRK09694; helicase Cas3; Provisional
    Support Center