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    FOXP1 forkhead box P1 [ Homo sapiens (human) ]

    Gene ID: 27086, updated on 8-Nov-2017
    Official Symbol
    FOXP1provided by HGNC
    Official Full Name
    forkhead box P1provided by HGNC
    Primary source
    HGNC:HGNC:3823
    See related
    Ensembl:ENSG00000114861 MIM:605515; Vega:OTTHUMG00000158803
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MFH; QRF1; 12CC4; hFKH1B; HSPC215
    Summary
    This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
    Orthologs
    Location:
    3p13
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 3 NC_000003.12 (70954714..71583989, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (71003865..71633140, complement)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene high mobility group box 1 pseudogene 36 Neighboring gene RNA, U6 small nuclear 281, pseudogene Neighboring gene FOXP1 antisense RNA 1 Neighboring gene microRNA 1284 Neighboring gene uncharacterized LOC105377155 Neighboring gene eukaryotic translation initiation factor 4E family member 3 Neighboring gene G protein-coupled receptor 27

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Associated conditions

    Description Tests
    Mental retardation with language impairment and with or without autistic features
    MedGen: C3150923 OMIM: 613670 GeneReviews: Not available
    Compare labs

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated (2013-04-11)

    ClinGen Genome Curation Page
    Haploinsufficency

    Sufficient evidence for dosage pathogenicity (Last evaluated (2013-04-11)

    ClinGen Genome Curation PagePubMed

    NHGRI GWAS Catalog

    Description
    A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
    NHGRI GWA Catalog
    Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
    NHGRI GWA Catalog
    Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
    NHGRI GWA Catalog
    Genome-wide association study and meta-analysis of intraocular pressure.
    NHGRI GWA Catalog
    Genome-wide meta-analysis identifies new susceptibility loci for migraine.
    NHGRI GWA Catalog
    Impact of ancestry and common genetic variants on QT interval in African Americans.
    NHGRI GWA Catalog
    Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
    NHGRI GWA Catalog
    • Developmental Biology, organism-specific biosystem (from REACTOME)
      Developmental Biology, organism-specific biosystemAs a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are a...
    • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
      MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
    • MicroRNAs in cancer, conserved biosystem (from KEGG)
      MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
    • Transcriptional regulation of pluripotent stem cells, organism-specific biosystem (from REACTOME)
      Transcriptional regulation of pluripotent stem cells, organism-specific biosystemPluripotent stem cells are undifferentiated cells posessing an abbreviated cell cycle (reviewed in Stein et al. 2012), a characteristic profile of gene expression (Rao et al. 2004, Kim et al. 2006, P...
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • FLJ23741, MGC12942, MGC88572, MGC99551

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    androgen receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein self-association IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    T follicular helper cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    chemokine (C-C motif) ligand 2 secretion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endothelial cell activation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    interleukin-21 secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    macrophage activation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    monocyte activation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of B cell apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of androgen receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    osteoclast development IDA
    Inferred from Direct Assay
    more info
    PubMed 
    osteoclast differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of endothelial cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of smooth muscle cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of defense response to bacterium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of endothelial tube morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of inflammatory response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of interleukin-1 beta secretion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of interleukin-12 secretion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of macrophage colony-stimulating factor production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of monocyte differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription from RNA polymerase II promoter IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of tumor necrosis factor production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to lipopolysaccharide IDA
    Inferred from Direct Assay
    more info
    PubMed 
    somatic stem cell population maintenance TAS
    Traceable Author Statement
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    nucleoplasm TAS
    Traceable Author Statement
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    forkhead box protein P1
    Names
    fork head-related protein like B
    glutamine-rich factor 1
    mac-1-regulated forkhead

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_028243.1 RefSeqGene

      Range
      5001..634276
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001012505.1NP_001012523.1  forkhead box protein P1 isoform b

      See identical proteins and their annotated locations for NP_001012523.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks multiple 3' exons but has an alternate exon in the 3' end, compared to variant 1. The encoded isoform b (previously called isoform 2) has a shorter and distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AC097634, BC005055, BC068481
      Consensus CDS
      CCDS33785.1
      UniProtKB/Swiss-Prot
      Q9H334
      Related
      ENSP00000318721.3, OTTHUMP00000213508, ENST00000318779.7, OTTHUMT00000352262
    2. NM_001244808.1NP_001231737.1  forkhead box protein P1 isoform c

      See identical proteins and their annotated locations for NP_001231737.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (c, previously called 3) has the same N- and C-termini but is 1 aa shorter compared to isoform a.
      Source sequence(s)
      AC103586, AK122710, BC068481, GD144178
      Consensus CDS
      CCDS58839.1
      UniProtKB/Swiss-Prot
      Q9H334
      Related
      ENSP00000418524.1, OTTHUMP00000213500, ENST00000493089.5, OTTHUMT00000352251
      Conserved Domains (2) summary
      cd00059
      Location:464536
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    3. NM_001244810.1NP_001231739.1  forkhead box protein P1 isoform d

      See identical proteins and their annotated locations for NP_001231739.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon but contains another compared to variant 1. The resulting isoform (d, previously called 4) has the same N- and C-termini but is longer compared to isoform a. This variant encodes the longest isoform, which has been shown to enhance embryonic stem (ES) cell pluripotency and repress ES cell differentiation.
      Source sequence(s)
      AC097634, AC103586, AK122710, BC054505, BC068481, GD144178
      Consensus CDS
      CCDS74964.1
      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      A0A087X299
      Related
      ENSP00000484803.1, ENST00000615603.4
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    4. NM_001244812.1NP_001231741.1  forkhead box protein P1 isoform e

      See identical proteins and their annotated locations for NP_001231741.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and lacks an alternate in-frame segment compared to variant 1. The resulting isoform (e, previously called 5) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AA380962, AC103586, AK092383, GD144178
      Consensus CDS
      CCDS58838.1
      UniProtKB/Swiss-Prot
      Q9H334
      Related
      ENSP00000417857.1, OTTHUMP00000213503, ENST00000484350.5, OTTHUMT00000352254
      Conserved Domains (2) summary
      cd00059
      Location:389461
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:226293
      FOXP-CC; FOXP coiled-coil domain
    5. NM_001244813.1NP_001231742.1  forkhead box protein P1 isoform f

      See identical proteins and their annotated locations for NP_001231742.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (f, previously called 6) is shorter at the N-terminus compared to isoform a.
      Source sequence(s)
      AC103586, AK074569, GD144178
      Consensus CDS
      CCDS74963.1
      UniProtKB/TrEMBL
      A0A0B4J2F3, Q8N2P0
      Related
      ENSP00000482847.1, ENST00000614176.4
      Conserved Domains (2) summary
      cd00059
      Location:365437
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:202269
      FOXP-CC; FOXP coiled-coil domain
    6. NM_001244814.1NP_001231743.1  forkhead box protein P1 isoform a

      See identical proteins and their annotated locations for NP_001231743.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1, 7, 9 and 11-13 all encode the same isoform (a).
      Source sequence(s)
      AC097632, AC103586, AK074321, DA518749, GD144178
      Consensus CDS
      CCDS2914.1
      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7, Q8TEA2
      Related
      ENSP00000418102.1, OTTHUMP00000213504, ENST00000498215.5, OTTHUMT00000352255
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    7. NM_001244815.1NP_001231744.1  forkhead box protein P1 isoform g

      See identical proteins and their annotated locations for NP_001231744.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (g, previously called 8) has a longer and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AC103586, AK027264, DA634017, GD144178
      Consensus CDS
      CCDS58837.1
      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      E9PFD3
      Related
      ENSP00000420736.1, OTTHUMP00000213506, ENST00000491238.5, OTTHUMT00000352260
      Conserved Domains (2) summary
      cd00059
      Location:467539
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:304371
      FOXP-CC; FOXP coiled-coil domain
    8. NM_001244816.1NP_001231745.1  forkhead box protein P1 isoform a

      See identical proteins and their annotated locations for NP_001231745.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 1. Variants 1, 7, 9, and 11-13 all encode the same isoform (a).
      Source sequence(s)
      AC103586, AF250920, GD144178
      Consensus CDS
      CCDS2914.1
      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Related
      ENSP00000419393.1, OTTHUMP00000213502, ENST00000475937.5, OTTHUMT00000352253
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    9. NM_001349337.1NP_001336266.1  forkhead box protein P1 isoform h

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10) encodes isoform h.
      Source sequence(s)
      AC097632, AC103586
      Conserved Domains (2) summary
      cd00059
      Location:466538
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:303370
      FOXP-CC; FOXP coiled-coil domain
    10. NM_001349338.1NP_001336267.1  forkhead box protein P1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 1, 7, 9, 12, and 13, encodes isoform a.
      Source sequence(s)
      AC097632, AC097634, AC103586, AC104442, AC104645, AC138058
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    11. NM_001349339.1NP_001336268.1  forkhead box protein P1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variants 1, 7, 9, 11, and 13, encodes isoform a.
      Source sequence(s)
      AC097632, AC097634, AC103586, AC104442, AC104645, AC138058
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    12. NM_001349340.1NP_001336269.1  forkhead box protein P1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13), as well as variants 1, 7, 9, 11, and 12, encodes isoform a.
      Source sequence(s)
      AC097632, AC097634, AC103586, AC104442, AC104645, AC138058
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    13. NM_001349341.1NP_001336270.1  forkhead box protein P1 isoform j

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14) encodes isoform j.
      Source sequence(s)
      AC097632, AC097634, AC103586, AC104442, AC104645, AC138058
      Conserved Domains (2) summary
      cd00059
      Location:464536
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:301368
      FOXP-CC; FOXP coiled-coil domain
    14. NM_001349342.1NP_001336271.1  forkhead box protein P1 isoform f

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15), as well as variant 6, encodes isoform f.
      Source sequence(s)
      AC097632, AC103586
      Conserved Domains (2) summary
      cd00059
      Location:365437
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:202269
      FOXP-CC; FOXP coiled-coil domain
    15. NM_001349343.1NP_001336272.1  forkhead box protein P1 isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16), as well as variant 17, encodes isoform i.
      Source sequence(s)
      AC097632, AC103586
      Conserved Domains (2) summary
      cd00059
      Location:364436
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:201268
      FOXP-CC; FOXP coiled-coil domain
    16. NM_001349344.1NP_001336273.1  forkhead box protein P1 isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17), as well as variant 16, encodes isoform i.
      Source sequence(s)
      AC097632, AC103586
      Conserved Domains (2) summary
      cd00059
      Location:364436
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:201268
      FOXP-CC; FOXP coiled-coil domain
    17. NM_032682.5NP_116071.2  forkhead box protein P1 isoform a

      See identical proteins and their annotated locations for NP_116071.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform a (previously called isoform 1). Variants 1, 7, 9, and 11-13 all encode the same isoform (a).
      Source sequence(s)
      AC097634, AC103586, AK122710, BC068481, GD144178
      Consensus CDS
      CCDS2914.1
      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Related
      ENSP00000318902.4, OTTHUMP00000213499, ENST00000318789.8, OTTHUMT00000352250
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain

    RNA

    1. NR_146142.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC097632, AC097634, AC103586, AC104442, AC104645, AC138058
    2. NR_146143.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC097632, AC097634, AC103586, AC104442, AC104645, AC138058

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p7 Primary Assembly

      Range
      70954714..71583989 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006713102.2XP_006713165.1  forkhead box protein P1 isoform X3

      See identical proteins and their annotated locations for XP_006713165.1

      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    2. XM_011533585.2XP_011531887.1  forkhead box protein P1 isoform X3

      See identical proteins and their annotated locations for XP_011531887.1

      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    3. XM_011533584.2XP_011531886.1  forkhead box protein P1 isoform X3

      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    4. XM_017006165.1XP_016861654.1  forkhead box protein P1 isoform X3

      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    5. XM_005264737.4XP_005264794.1  forkhead box protein P1 isoform X5

      Conserved Domains (2) summary
      cd00059
      Location:464536
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:301368
      FOXP-CC; FOXP coiled-coil domain
    6. XM_017006166.1XP_016861655.1  forkhead box protein P1 isoform X3

      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    7. XM_006713104.2XP_006713167.1  forkhead box protein P1 isoform X3

      See identical proteins and their annotated locations for XP_006713167.1

      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    8. XM_006713103.2XP_006713166.1  forkhead box protein P1 isoform X3

      See identical proteins and their annotated locations for XP_006713166.1

      UniProtKB/Swiss-Prot
      Q9H334
      UniProtKB/TrEMBL
      Q548T7
      Related
      ENSP00000418883.1, OTTHUMP00000213507, ENST00000468577.5, OTTHUMT00000352261
      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:302369
      FOXP-CC; FOXP coiled-coil domain
    9. XM_011533588.2XP_011531890.1  forkhead box protein P1 isoform X6

      UniProtKB/TrEMBL
      A0A0B4J2F3
      Conserved Domains (2) summary
      cd00059
      Location:365437
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:202269
      FOXP-CC; FOXP coiled-coil domain
    10. XM_017006167.1XP_016861656.1  forkhead box protein P1 isoform X4

      Conserved Domains (2) summary
      cd00059
      Location:465537
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:303370
      FOXP-CC; FOXP coiled-coil domain
    11. XM_005264736.3XP_005264793.1  forkhead box protein P1 isoform X2

      See identical proteins and their annotated locations for XP_005264793.1

      Conserved Domains (2) summary
      cd00059
      Location:466538
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:304371
      FOXP-CC; FOXP coiled-coil domain
    12. XM_005264735.3XP_005264792.1  forkhead box protein P1 isoform X1

      Related
      ENSP00000418225.1, OTTHUMP00000213505, ENST00000497355.5, OTTHUMT00000352258
      Conserved Domains (2) summary
      cd00059
      Location:466538
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:303370
      FOXP-CC; FOXP coiled-coil domain
    13. XM_005264742.3XP_005264799.1  forkhead box protein P1 isoform X7

      Conserved Domains (2) summary
      cd00059
      Location:364436
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16159
      Location:201268
      FOXP-CC; FOXP coiled-coil domain
    14. XM_017006168.1XP_016861657.1  forkhead box protein P1 isoform X8

      UniProtKB/Swiss-Prot
      Q9H334

    RNA

    1. XR_001740102.1 RNA Sequence

    Alternate CHM1_1.1

    Genomic

    1. NC_018914.2 Alternate CHM1_1.1

      Range
      70955452..71584748 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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