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    JHDM2 JmjC domain-containing histone demethylase 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41143, updated on 7-May-2017
    Official Symbol
    JHDM2provided by FlyBase
    Official Full Name
    JmjC domain-containing histone demethylase 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0037703
    Locus tag
    Dmel_CG8165
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31123; CG8165; Dmel\CG8165
    Location:
    85D19-85D19
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9516007..9520938)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5341729..5346660)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Ras oncogene at 85D Neighboring gene CG8161 gene product from transcript CG8161-RA Neighboring gene mitochondrial ribosomal protein L47 Neighboring gene CG8176 gene product from transcript CG8176-RF Neighboring gene mir-2283 stem loop Neighboring gene blistery Neighboring gene murashka Neighboring gene ncRNA

    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    chromatin DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    histone demethylase activity ISM
    Inferred from Sequence Model
    more info
    PubMed 
    histone demethylase activity (H3-K9 specific) IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    histone H3-K9 demethylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    histone demethylation ISM
    Inferred from Sequence Model
    more info
    PubMed 
    positive regulation of chromatin silencing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of response to DNA damage stimulus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleus ISM
    Inferred from Sequence Model
    more info
    PubMed 
    Preferred Names
    CG8165 gene product from transcript CG8165-RA
    Names
    CG8165-PA
    CG8165-PB
    JHDM2-PA
    JHDM2-PB
    JmjC domain-containing histone demethylase 2

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9516007..9520938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176434.2NP_788611.1  JmjC domain-containing histone demethylase 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788611.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHC5
      Related
      FBpp0081541, FBtr0082063
      Conserved Domains (2) summary
      smart00558
      Location:605657
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      cl21464
      Location:694789
      cupin_like; Conserved domain found in cupin and related proteins
    2. NM_001300326.1NP_001287255.1  JmjC domain-containing histone demethylase 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287255.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VHC5
      Related
      FBpp0311387, FBtr0345178
      Conserved Domains (2) summary
      smart00558
      Location:605657
      JmjC; A domain family that is part of the cupin metalloenzyme superfamily
      cl21464
      Location:694789
      cupin_like; Conserved domain found in cupin and related proteins
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