Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Afp alpha fetoprotein [ Mus musculus (house mouse) ]

    Gene ID: 11576, updated on 22-Apr-2017
    Official Symbol
    Afpprovided by MGI
    Official Full Name
    alpha fetoproteinprovided by MGI
    Primary source
    MGI:MGI:87951
    See related
    Ensembl:ENSMUSG00000054932 Vega:OTTMUSG00000055486
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Orthologs
    Location:
    5 E1; 5 44.77 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (90490714..90508907)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (90919740..90937933)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 35999 Neighboring gene albumin Neighboring gene afamin Neighboring gene zinc finger, BED domain containing 4 pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Hippo signaling pathway, organism-specific biosystem (from KEGG)
      Hippo signaling pathway, organism-specific biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...
    • Hippo signaling pathway, conserved biosystem (from KEGG)
      Hippo signaling pathway, conserved biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    beta-glucuronidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    SMAD protein signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ovulation from ovarian follicle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    progesterone metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sexual reproduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    alpha-fetoprotein
    Names
    alpha-1-fetoprotein
    alpha-fetoglobulin
    alpha-foetoprotein

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007423.4NP_031449.3  alpha-fetoprotein precursor

      See identical proteins and their annotated locations for NP_031449.3

      Status: VALIDATED

      Source sequence(s)
      AV105248, BC066206, BY773400
      Consensus CDS
      CCDS19413.1
      UniProtKB/Swiss-Prot
      P02772
      Related
      ENSMUSP00000041006.3, OTTMUSP00000072342, ENSMUST00000042755.6, OTTMUST00000137327
      Conserved Domains (1) summary
      smart00103
      Location:400590
      ALBUMIN; serum albumin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      90490714..90508907
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center