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    GR1 protein gamma response 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824375, updated on 14-Dec-2016
    Gene symbol
    GR1
    Gene description
    protein gamma response 1
    Primary source
    Araport:AT3G52115
    Locus tag
    AT3G52115
    Gene type
    protein coding
    RNA name
    protein gamma response 1
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCOM1; ATGR1; COM1; gamma response gene 1
    Summary
    Induced in response to ionizing radiation, shows basal expression in mitotically active cells and high expression in endoreduplicating cells. May be involved in DNA damage-induced growth arrest. Protein sequence contains a PEST destruction box.
    See GR1 in Map Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Sequence:
    Chromosome: 3; NC_003074.8 (19326035..19328379)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene DIS3-exonuclease-like protein Neighboring gene ncRNA Neighboring gene interferon-activable protein Neighboring gene ncRNA Neighboring gene SWAP (Suppressor-of-White-APricot)/surp domain-containing protein / D111/G-patch domain-containing protein Neighboring gene ncRNA Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene ncRNA

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NM_180352.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic DNA double-strand break processing IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    response to ionizing radiation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus ISM
    Inferred from Sequence Model
    more info
     
    Names
    protein gamma response 1
    NP_850683.1
    • gamma response gene 1 (GR1); INVOLVED IN: meiotic DNA double-strand break processing, response to DNA damage stimulus, gamete generation, response to ionizing radiation; EXPRESSED IN: bud, cultured cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: DNA repair protein Sae2/CtIP (InterPro:IPR013882); Has 26568 Blast hits to 17186 proteins in 1344 species: Archae - 485; Bacteria - 2739; Metazoa - 14510; Fungi - 2010; Plants - 1072; Viruses - 86; Other Eukaryotes - 5666 (source: NCBI BLink).

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19326035..19328379
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180352.3NP_850683.1  protein gamma response 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850683.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZRT1
      UniProtKB/TrEMBL
      A0A178V6G8
      Conserved Domains (2) summary
      pfam08573
      Location:517584
      SAE2; DNA repair protein endonuclease SAE2/CtIP C-terminus
      pfam14584
      Location:217272
      DUF4446; Protein of unknown function (DUF4446)
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