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    TRM2 Trm2p [ Saccharomyces cerevisiae S288c ]

    Gene ID: 853930, updated on 9-Apr-2017
    Gene symbol
    TRM2
    Gene description
    Trm2p
    Primary source
    SGD:S000001764
    Locus tag
    YKR056W
    Gene type
    protein coding
    RNA name
    Trm2p
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    NUC2; NUD1; RNC1
    See TRM2 in Map Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (549448..551367)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene dynein heavy chain Neighboring gene Rho family GTPase RHO4 Neighboring gene ribosomal 40S subunit protein S21A Neighboring gene glycogenin glucosyltransferase GLG1

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    RNA methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    double-stranded DNA 5'-3' exodeoxyribonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    single-stranded DNA endodeoxyribonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    tRNA (m5U54) methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    tRNA (m5U54) methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    DNA repair IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    RNA methylation IEA
    Inferred from Electronic Annotation
    more info
     
    RNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    double-strand break repair IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    double-strand break repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    methylation IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid phosphodiester bond hydrolysis IEA
    Inferred from Electronic Annotation
    more info
     
    tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
     
    tRNA modification IDA
    Inferred from Direct Assay
    more info
    PubMed 
    tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    Names
    Trm2p
    NP_012982.2
    • tRNA methyltransferase; 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      549448..551367
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179846.1NP_012982.2  TPA: Trm2p [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_012982.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P33753
      Conserved Domains (3) summary
      COG2265
      Location:166632
      TrmA; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]
      pfam01938
      Location:164227
      TRAM; TRAM domain
      cl17173
      Location:444639
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
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