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    tdgf1 teratocarcinoma-derived growth factor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 30304, updated on 3-Dec-2017
    Official Symbol
    tdgf1provided by ZNC
    Official Full Name
    teratocarcinoma-derived growth factor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990415-198
    See related
    Ensembl:ENSDARG00000035095
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    oep; cb85; cripto; wu:fe01d04; zgc:109829
    Location:
    chromosome: 10
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (1955474..1961930, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (1927760..1934216, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene adenomatous polyposis coli Neighboring gene C3a anaphylatoxin chemotactic receptor Neighboring gene uncharacterized LOC100535760 Neighboring gene uncharacterized LOC101884606

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    adrenal gland development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    brain morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cardioblast migration to the midline involved in heart field formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    central nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    convergent extension involved in gastrulation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    convergent extension involved in nephron morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    determination of left/right symmetry IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    digestive tract development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dorsal/ventral pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ectoderm development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endoderm formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    floor plate development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    floor plate formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    floor plate formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    forebrain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    germ cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hypoblast development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hypothalamus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    induction of positive chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mesendoderm development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mesoderm development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mesoderm formation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    mesoderm formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neural plate anterior/posterior regionalization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neural tube closure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    notochord development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    notochord morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    optic placode formation involved in camera-type eye formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    paraxial mesoderm development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    prechordal plate formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    pronephric glomerulus morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    retina development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    somite development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    somitogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    telencephalon development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    external side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    cryptic protein
    Names
    one-eyed pinhead

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328408.1NP_001315337.1  cryptic protein isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      BC152111, CABZ01070744
      UniProtKB/TrEMBL
      A7MCB2
      Related
      ENSDARP00000106724.1, ENSDART00000122446.2
      Conserved Domains (2) summary
      cd00054
      Location:84108
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam09443
      Location:116150
      CFC; Cripto_Frl-1_Cryptic (CFC)
    2. NM_131092.2NP_571167.2  cryptic protein isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      CABZ01070743, CABZ01070744
      UniProtKB/TrEMBL
      F1Q691
      Related
      ENSDARP00000091797.2, ENSDART00000101023.3

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      1955474..1961930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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