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    SPP1 secreted phosphoprotein 1 [ Ovis aries (sheep) ]

    Gene ID: 443058, updated on 8-Apr-2017
    Gene symbol
    SPP1
    Gene description
    secreted phosphoprotein 1
    See related
    Ensembl:ENSOARG00000002590
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ovis aries
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
    Also known as
    OPN
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    102 current Oar_v4.0 (GCF_000298735.2) 14 NC_019471.2 (23627690..23656933, complement)
    102 current Oar_v4.0 (GCF_000298735.2) 6 NC_019463.2 (36573369..36586285, complement)
    101 previous assembly Oar_v3.1 (GCF_000298735.1) 14 NC_019471.1 (23695520..23725459, complement)
    101 previous assembly Oar_v3.1 (GCF_000298735.1) 6 NC_019463.1 (36645289..36658205, complement)

    Chromosome 6 - NC_019463.2Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily G member 2 (Junior blood group) Neighboring gene polycystin 2, transient receptor potential cation channel Neighboring gene matrix extracellular phosphoglycoprotein Neighboring gene integrin binding sialoprotein

    Chromosome 14 - NC_019471.2Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase type IVA 1 pseudogene Neighboring gene 2-oxoglutarate and iron dependent oxygenase domain containing 1 Neighboring gene nudix hydrolase 21 Neighboring gene autocrine motility factor receptor Neighboring gene G protein subunit alpha o1 Neighboring gene uncharacterized LOC105608118

    • Apelin signaling pathway, organism-specific biosystem (from KEGG)
      Apelin signaling pathway, organism-specific biosystemApelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally described as an orphan G-protein-coupled receptor. Apelin and APJ are widely expressed in various ti...
    • ECM-receptor interaction, organism-specific biosystem (from KEGG)
      ECM-receptor interaction, organism-specific biosystemThe extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell ...
    • ECM-receptor interaction, conserved biosystem (from KEGG)
      ECM-receptor interaction, conserved biosystemThe extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell ...
    • Focal adhesion, organism-specific biosystem (from KEGG)
      Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • Focal adhesion, conserved biosystem (from KEGG)
      Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
      PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
    • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
      PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
    • Toll-like receptor signaling pathway, organism-specific biosystem (from KEGG)
      Toll-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors id...
    • Toll-like receptor signaling pathway, conserved biosystem (from KEGG)
      Toll-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting microbial pathogens and generating innate immune responses. Toll-like receptors (TLRs) are membrane-bound receptors id...
    Preferred Names
    osteopontin
    Names
    SPP-1
    bone sialoprotein 1
    secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009224.1NP_001009224.1  osteopontin precursor

      See identical proteins and their annotated locations for NP_001009224.1

      Status: PROVISIONAL

      Source sequence(s)
      AF152416
      UniProtKB/Swiss-Prot
      Q9XSY9
      Related
      ENSOARP00000002753, ENSOART00000002808
      Conserved Domains (1) summary
      smart00017
      Location:17278
      OSTEO; Osteopontin

    RefSeqs of Annotated Genomes: Ovis aries Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Oar_v4.0 Primary Assembly

    Genomic

    1. NC_019463.2 Reference Oar_v4.0 Primary Assembly

      Range
      36573369..36586285 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference Oar_v4.0 Primary Assembly

    Genomic

    1. NC_019471.2 Reference Oar_v4.0 Primary Assembly

      Range
      23627690..23656933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Oori1

    Genomic

    1. NW_011942326.1 Alternate Oori1

      Range
      484465..513857
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Oori1

    Genomic

    1. NW_011943592.1 Alternate Oori1

      Range
      285369..298303 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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