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    priA Primosome factor n' (replication factor Y) [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948426, updated on 18-Apr-2017
    Gene symbol
    priA
    Gene description
    Primosome factor n' (replication factor Y)
    Primary source
    EcoGene:EG10763
    Locus tag
    b3935
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3927; JW3906; srgA
    Summary
    The role of PriA in the cell appears to be the restart of stalled replication forks. [More information is available at EcoCyc: EG10763].
    Sequence:
    NC_000913.3 (4124612..4126810, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene essential cell division protein Neighboring gene Anti-activator for CytR-CRP nucleoside utilization regulon Neighboring gene 50S ribosomal subunit protein L31 Neighboring gene putative lipid binding hydrolase, DUF830 family protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Homologous recombination, organism-specific biosystem (from KEGG)
      Homologous recombination, organism-specific biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...
    • Homologous recombination, conserved biosystem (from KEGG)
      Homologous recombination, conserved biosystemHomologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves...
    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP-dependent 3'-5' DNA helicase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    helicase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA recombination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    DNA replication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    DNA replication initiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    DNA unwinding involved in DNA replication IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-dependent DNA replication IDA
    Inferred from Direct Assay
    more info
    PubMed 
    double-strand break repair IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    plasmid maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to antibiotic IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to gamma radiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Names
    Primosome factor n' (replication factor Y)
    NP_418370.1
    • primosomal protein N'(= factor Y)(putative helicase)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4124612..4126810 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418370.1 Primosome factor n' (replication factor Y) [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418370.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P17888
      Conserved Domains (3) summary
      smart00490
      Location:492589
      HELICc; helicase superfamily c-terminal domain
      PRK05580
      Location:1731
      PRK05580; primosome assembly protein PriA; Validated
      pfam00270
      Location:203359
      DEAD; DEAD/DEAH box helicase
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