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    Sod1 superoxide dismutase 1, soluble [ Mus musculus (house mouse) ]

    Gene ID: 20655, updated on 15-Oct-2017
    Official Symbol
    Sod1provided by MGI
    Official Full Name
    superoxide dismutase 1, solubleprovided by MGI
    Primary source
    MGI:MGI:98351
    See related
    Ensembl:ENSMUSG00000022982
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ipo1; SODC; Ipo-1; Sod-1; CuZnSOD; Cu/Zn-SOD; B430204E11Rik
    Orthologs
    Location:
    16 C3.3; 16 51.56 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (90220742..90226324)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (90220987..90226569)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene ferritin light chain 1 pseudogene Neighboring gene predicted gene, 35714 Neighboring gene SR-related CTD-associated factor 4 Neighboring gene hormonally upregulated Neu-associated kinase

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (6)  1 citation
    • Chemically induced (ENU) (1) 
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC107553

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Rac GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    antioxidant activity IEA
    Inferred from Electronic Annotation
    more info
     
    chaperone binding ISO
    Inferred from Sequence Orthology
    more info
     
    copper ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    copper ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein phosphatase 2B binding ISO
    Inferred from Sequence Orthology
    more info
     
    superoxide dismutase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    superoxide dismutase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    superoxide dismutase activity ISO
    Inferred from Sequence Orthology
    more info
     
    superoxide dismutase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    activation of MAPK activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    aging IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    anterograde axonal transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    auditory receptor cell stereocilium organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell aging ISO
    Inferred from Sequence Orthology
    more info
     
    cellular iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryo implantation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glutathione metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart contraction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart contraction ISO
    Inferred from Sequence Orthology
    more info
     
    hydrogen peroxide biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hydrogen peroxide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    locomotory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    muscle cell cellular homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    myeloid cell homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    myeloid cell homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cholesterol biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neurofilament cytoskeleton organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    neurofilament cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ovarian follicle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    peripheral nervous system myelin maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of catalytic activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytokine production ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of superoxide anion generation ISO
    Inferred from Sequence Orthology
    more info
     
    reactive oxygen species metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of blood pressure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of mitochondrial membrane potential ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of multicellular organism growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    relaxation of vascular smooth muscle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    removal of superoxide radicals IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    removal of superoxide radicals IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    removal of superoxide radicals ISO
    Inferred from Sequence Orthology
    more info
     
    removal of superoxide radicals TAS
    Traceable Author Statement
    more info
    PubMed 
    response to axon injury IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to copper ion ISO
    Inferred from Sequence Orthology
    more info
     
    response to drug IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to heat IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to hydrogen peroxide IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to nutrient levels ISO
    Inferred from Sequence Orthology
    more info
     
    response to organic substance ISO
    Inferred from Sequence Orthology
    more info
     
    response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to oxidative stress ISO
    Inferred from Sequence Orthology
    more info
     
    response to reactive oxygen species IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to superoxide IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to superoxide ISO
    Inferred from Sequence Orthology
    more info
     
    retina homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    retrograde axonal transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sensory perception of sound IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    superoxide anion generation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    superoxide metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    superoxide metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    transmission of nerve impulse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    dense core granule ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial intermembrane space ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    myelin sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    secretory granule ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    superoxide dismutase [Cu-Zn]
    Names
    Cu(2+)-Zn2+ superoxide dismutase
    NP_035564.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011434.1NP_035564.1  superoxide dismutase [Cu-Zn]

      See identical proteins and their annotated locations for NP_035564.1

      Status: PROVISIONAL

      Source sequence(s)
      BC048874
      Consensus CDS
      CCDS37395.1
      UniProtKB/Swiss-Prot
      P08228
      Related
      ENSMUSP00000023707.9, ENSMUST00000023707.9
      Conserved Domains (1) summary
      pfam00080
      Location:11150
      Sod_Cu; Copper/zinc superoxide dismutase (SODC)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      90220742..90226324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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