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    HCRTR2 hypocretin receptor 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 399545, updated on 25-May-2017
    Gene symbol
    HCRTR2
    Gene description
    hypocretin receptor 2
    See related
    Ensembl:ENSCAFG00000002328
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    Location:
    chromosome: 12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    104 current CanFam3.1 (GCF_000002285.3) 12 NC_006594.3 (22517482..22623358)

    Chromosome 12 - NC_006594.3Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83 member B Neighboring gene H/ACA ribonucleoprotein complex subunit 3 pseudogene Neighboring gene GDNF family receptor alpha like Neighboring gene 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1

    Genomic Sequence:
    NC_006594.3 Chromosome 12 Reference CanFam3.1 Primary Assembly

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    orexin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    orexin receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    cellular response to hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    circadian sleep/wake cycle process IEA
    Inferred from Electronic Annotation
    more info
     
    feeding behavior IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neuropeptide signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neuropeptide signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phospholipase C-activating G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of circadian sleep/wake cycle, sleep IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    regulation of circadian sleep/wake cycle, wakefulness IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cytosolic calcium ion concentration IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cytosolic calcium ion concentration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to peptide IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    integral component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Preferred Names
    orexin receptor type 2
    Names
    hypocretin receptor type 2
    hypocretin/orexin (Hcrt) receptor 2
    ox-2-R
    ox2-R
    ox2R

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002933.1NP_001002933.1  orexin receptor type 2

      See identical proteins and their annotated locations for NP_001002933.1

      Status: PROVISIONAL

      Source sequence(s)
      AF164626
      UniProtKB/Swiss-Prot
      Q9TUP7
      Related
      ENSCAFP00000003376.1, ENSCAFT00000003647.1
      Conserved Domains (3) summary
      pfam00001
      Location:71364
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      pfam03827
      Location:387444
      Orexin_rec2; Orexin receptor type 2
      cl21561
      Location:65194
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006594.3 Reference CanFam3.1 Primary Assembly

      Range
      22517482..22623358
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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