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    YHR214C-B gag-pol fusion protein [ Saccharomyces cerevisiae S288c ]

    Gene ID: 856623, updated on 9-Apr-2017
    Gene symbol
    YHR214C-B
    Gene description
    gag-pol fusion protein
    Primary source
    SGD:S000003534
    Locus tag
    YHR214C-B
    Gene type
    protein coding
    RNA name
    gag-pol fusion protein
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288c (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    See YHR214C-B in Map Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (543964..549346, complement)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene gag protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

    Products Interactant Other Gene Complex Source Pubs Description

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-directed DNA polymerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    RNA-DNA hybrid ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    RNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    RNA-directed DNA polymerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    ribonuclease activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    DNA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    DNA integration IEA
    Inferred from Electronic Annotation
    more info
     
    DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    RNA phosphodiester bond hydrolysis IEA
    Inferred from Electronic Annotation
    more info
     
    RNA phosphodiester bond hydrolysis, endonucleolytic IEA
    Inferred from Electronic Annotation
    more info
     
    RNA-dependent DNA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid phosphodiester bond hydrolysis IEA
    Inferred from Electronic Annotation
    more info
     
    proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    transposition IEA
    Inferred from Electronic Annotation
    more info
     
    transposition, RNA-mediated ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    retrotransposon nucleocapsid ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Names
    gag-pol fusion protein
    NP_012086.1
    • Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes; YHR214C-B has a paralog, YAR070C, that arose from a segmental duplication

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      543964..549346 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181431.2NP_012086.1  TPA: gag-pol fusion protein [Saccharomyces cerevisiae S288c]

      See identical proteins and their annotated locations for NP_012086.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O13535
      Conserved Domains (4) summary
      cd09272
      Location:16441780
      RNase_HI_RT_Ty1; Ty1/Copia family of RNase HI in long-term repeat retroelements
      pfam00665
      Location:702820
      rve; Integrase core domain
      pfam01021
      Location:17114
      TYA; TYA transposon protein
      pfam07727
      Location:13031532
      RVT_2; Reverse transcriptase (RNA-dependent DNA polymerase)
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