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    Ido2 indoleamine 2,3-dioxygenase 2 [ Mus musculus (house mouse) ]

    Gene ID: 209176, updated on 20-Aug-2017
    Official Symbol
    Ido2provided by MGI
    Official Full Name
    indoleamine 2,3-dioxygenase 2provided by MGI
    Primary source
    MGI:MGI:2142489
    See related
    Ensembl:ENSMUSG00000031549 Vega:OTTMUSG00000029868
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ido-2; Indol1; AI265623; C230043N17Rik
    Orthologs
    Location:
    8; 8 A2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (24531892..24576408, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (25642364..25686805, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30845 Neighboring gene uncharacterized LOC102632957 Neighboring gene indoleamine 2,3-dioxygenase 1 Neighboring gene a disintegrin and metallopeptidase domain 18

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC31194

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    dioxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    indoleamine 2,3-dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    indoleamine 2,3-dioxygenase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    indoleamine 2,3-dioxygenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    tryptophan 2,3-dioxygenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    tryptophan catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    tryptophan catabolic process to kynurenine IDA
    Inferred from Direct Assay
    more info
    PubMed 
    tryptophan catabolic process to kynurenine IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    tryptophan catabolic process to kynurenine ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    indoleamine 2,3-dioxygenase 2
    Names
    indoleamine 2,3-dioxygenase-like protein 1
    indoleamine-pyrrole 2,3 dioxygenase-like 1
    NP_666061.3
    XP_006509109.1
    XP_006509110.1
    XP_006509111.1
    XP_011240433.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145949.2NP_666061.3  indoleamine 2,3-dioxygenase 2

      See identical proteins and their annotated locations for NP_666061.3

      Status: VALIDATED

      Source sequence(s)
      AC114602, BX637885, EF137182
      Consensus CDS
      CCDS40298.2
      UniProtKB/Swiss-Prot
      Q8R0V5
      Related
      ENSMUSP00000113979.1, OTTMUSP00000038470, ENSMUST00000121992.1, OTTMUST00000074117
      Conserved Domains (1) summary
      pfam01231
      Location:15399
      IDO; Indoleamine 2,3-dioxygenase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      24531892..24576408 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509046.3XP_006509109.1  indoleamine 2,3-dioxygenase 2 isoform X1

      Conserved Domains (1) summary
      pfam01231
      Location:38367
      IDO; Indoleamine 2,3-dioxygenase
    2. XM_006509047.2XP_006509110.1  indoleamine 2,3-dioxygenase 2 isoform X2

      See identical proteins and their annotated locations for XP_006509110.1

      Conserved Domains (1) summary
      pfam01231
      Location:1334
      IDO; Indoleamine 2,3-dioxygenase
    3. XM_006509048.2XP_006509111.1  indoleamine 2,3-dioxygenase 2 isoform X2

      See identical proteins and their annotated locations for XP_006509111.1

      Conserved Domains (1) summary
      pfam01231
      Location:1334
      IDO; Indoleamine 2,3-dioxygenase
    4. XM_011242131.2XP_011240433.1  indoleamine 2,3-dioxygenase 2 isoform X3

      Conserved Domains (1) summary
      cl21721
      Location:15240
      IDO; Indoleamine 2,3-dioxygenase
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