Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    EDN1 endothelin 1 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100009270, updated on 3-Apr-2017
    Gene symbol
    EDN1
    Gene description
    endothelin 1
    See related
    Ensembl:ENSOCUG00000013396
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Also known as
    ET-1
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    102 current OryCun2.0 (GCF_000003625.3) 12 NC_013680.1 (6011333..6037477)

    Chromosome 12 - NC_013680.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103349680 Neighboring gene human immunodeficiency virus type I enhancer binding protein 1 Neighboring gene phosphatase and actin regulator 1 Neighboring gene 60S ribosomal protein L7 pseudogene Neighboring gene TBC1 domain family member 7

    Genomic Sequence:
    NC_013680.1 Chromosome 12 Reference OryCun2.0 Primary Assembly

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • AGE-RAGE signaling pathway in diabetic complications, organism-specific biosystem (from KEGG)
      AGE-RAGE signaling pathway in diabetic complications, organism-specific biosystemAdvanced glycation end products (AGEs) are a complex group of compounds produced through the non-enzymatic glycation and oxidation of proteins, lipids and nucleic acids, primarily due to aging and un...
    • AGE-RAGE signaling pathway in diabetic complications, conserved biosystem (from KEGG)
      AGE-RAGE signaling pathway in diabetic complications, conserved biosystemAdvanced glycation end products (AGEs) are a complex group of compounds produced through the non-enzymatic glycation and oxidation of proteins, lipids and nucleic acids, primarily due to aging and un...
    • Fluid shear stress and atherosclerosis, organism-specific biosystem (from KEGG)
      Fluid shear stress and atherosclerosis, organism-specific biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
    • Fluid shear stress and atherosclerosis, conserved biosystem (from KEGG)
      Fluid shear stress and atherosclerosis, conserved biosystemShear stress represents the frictional force that the flow of blood exerts at the endothelial surface of the vessel wall and plays a central role in vascular biology and contributes to the progress o...
    • HIF-1 signaling pathway, organism-specific biosystem (from KEGG)
      HIF-1 signaling pathway, organism-specific biosystemHypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. It consists of two subunits: an inducibly-expressed HIF-1alpha subunit and a c...
    • Melanogenesis, organism-specific biosystem (from KEGG)
      Melanogenesis, organism-specific biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • Melanogenesis, conserved biosystem (from KEGG)
      Melanogenesis, conserved biosystemCutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory cont...
    • TNF signaling pathway, organism-specific biosystem (from KEGG)
      TNF signaling pathway, organism-specific biosystemTumor necrosis factor (TNF), as a critical cytokine, can induce a wide range of intracellular signal pathways including apoptosis and cell survival as well as inflammation and immunity. Activated TNF...
    • TNF signaling pathway, conserved biosystem (from KEGG)
      TNF signaling pathway, conserved biosystemTumor necrosis factor (TNF), as a critical cytokine, can induce a wide range of intracellular signal pathways including apoptosis and cell survival as well as inflammation and immunity. Activated TNF...
    Preferred Names
    endothelin-1
    Names
    PPET1
    preproendothelin-1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001101696.1NP_001095166.1  endothelin-1 precursor

      See identical proteins and their annotated locations for NP_001095166.1

      Status: PROVISIONAL

      Source sequence(s)
      X59931
      UniProtKB/Swiss-Prot
      P29560
      Related
      ENSOCUP00000011526.2, ENSOCUT00000013396.3
      Conserved Domains (2) summary
      smart00272
      Location:109130
      END; Endothelin
      pfam00322
      Location:4977
      Endothelin; Endothelin family

    RefSeqs of Annotated Genomes: Oryctolagus cuniculus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference OryCun2.0 Primary Assembly

    Genomic

    1. NC_013680.1 Reference OryCun2.0 Primary Assembly

      Range
      6011333..6037477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center