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    RAPGEF6 Rap guanine nucleotide exchange factor 6 [ Mustela putorius furo (domestic ferret) ]

    Gene ID: 101671556, updated on 3-Apr-2017
    Gene symbol
    RAPGEF6
    Gene description
    Rap guanine nucleotide exchange factor 6
    See related
    Ensembl:ENSMPUG00000011611
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Mustela putorius furo (sub-species: furo)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Mustelidae; Mustelinae; Mustela
    Orthologs
    Location:
    chromosome: Un
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    101 current MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004569142.1 (400705..596522)

    NW_004569142.1Genomic Context describing neighboring genes Neighboring gene folliculin interacting protein 1 Neighboring gene heterogeneous nuclear ribonucleoprotein K pseudogene Neighboring gene uncharacterized LOC106005545 Neighboring gene uncharacterized LOC101673699 Neighboring gene plakophilin-4 pseudogene

    Genomic Sequence:
    NW_004569142.1 Unplaced Scaffold Reference MusPutFur1.0 Primary Assembly

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Preferred Names
    rap guanine nucleotide exchange factor 6

    RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference MusPutFur1.0 Primary Assembly

    Genomic

    1. NW_004569142.1 Reference MusPutFur1.0 Primary Assembly

      Range
      400705..596522
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004737410.2XP_004737467.1  rap guanine nucleotide exchange factor 6 isoform X1

      Conserved Domains (6) summary
      smart00229
      Location:412525
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00038
      Location:280380
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00155
      Location:8571081
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00992
      Location:529609
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00047
      Location:3782
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cl00155
      Location:749833
      UBQ; Ubiquitin-like proteins
    2. XM_004737414.2XP_004737471.1  rap guanine nucleotide exchange factor 6 isoform X4

      Conserved Domains (6) summary
      smart00229
      Location:412525
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00038
      Location:280380
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00155
      Location:8571081
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00992
      Location:529609
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00047
      Location:3782
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cl00155
      Location:749833
      UBQ; Ubiquitin-like proteins
    3. XM_004737411.2XP_004737468.1  rap guanine nucleotide exchange factor 6 isoform X2

      Related
      ENSMPUP00000011519.1, ENSMPUT00000011709.1
      Conserved Domains (6) summary
      smart00229
      Location:412525
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00038
      Location:280380
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00155
      Location:8571067
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00992
      Location:529609
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00047
      Location:3782
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cl00155
      Location:749833
      UBQ; Ubiquitin-like proteins
    4. XM_013054709.1XP_012910163.1  rap guanine nucleotide exchange factor 6 isoform X6

      Conserved Domains (6) summary
      smart00229
      Location:412525
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00038
      Location:280380
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00155
      Location:8571081
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00992
      Location:529609
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00047
      Location:3782
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cl00155
      Location:749833
      UBQ; Ubiquitin-like proteins
    5. XM_004737418.2XP_004737475.1  rap guanine nucleotide exchange factor 6 isoform X7

      Conserved Domains (6) summary
      smart00229
      Location:412525
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00038
      Location:280380
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00155
      Location:8571067
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00992
      Location:529609
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00047
      Location:3782
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cl00155
      Location:749833
      UBQ; Ubiquitin-like proteins
    6. XM_004737413.2XP_004737470.1  rap guanine nucleotide exchange factor 6 isoform X3

      Conserved Domains (5) summary
      smart00229
      Location:317430
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00038
      Location:185285
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00155
      Location:762986
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00992
      Location:434514
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00155
      Location:654738
      UBQ; Ubiquitin-like proteins
    7. XM_004737417.2XP_004737474.1  rap guanine nucleotide exchange factor 6 isoform X5

      Conserved Domains (5) summary
      smart00229
      Location:265378
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00038
      Location:133233
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cd00155
      Location:710934
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd00992
      Location:382462
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cl00155
      Location:602686
      UBQ; Ubiquitin-like proteins
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