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    Sox3 SRY (sex determining region Y)-box 3 [ Mus musculus (house mouse) ]

    Gene ID: 20675, updated on 8-Apr-2018
    Official Symbol
    Sox3provided by MGI
    Official Full Name
    SRY (sex determining region Y)-box 3provided by MGI
    Primary source
    MGI:MGI:98365
    See related
    Ensembl:ENSMUSG00000045179 Vega:OTTMUSG00000017611
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sox-3
    Orthologs
    Location:
    X A6; X 33.66 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (60891366..60893430, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (58144541..58146605, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene predicted gene 14661 Neighboring gene within bgcn homolog pseudogene Neighboring gene predicted gene, 38438 Neighboring gene ribosomal protein L7-like 1, pseudogene 1 Neighboring gene estrogen related receptor, beta pseudogene

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II core promoter sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    Sertoli cell development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    animal organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    face development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    forebrain development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hypothalamus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    pituitary gland development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    sensory organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sex determination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sex determination ISO
    Inferred from Sequence Orthology
    more info
     
    spermatid differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    transcription factor SOX-3
    Names
    SRY-box containing gene 3

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009237.2NP_033263.2  transcription factor SOX-3

      Status: VALIDATED

      Source sequence(s)
      AL807233, BC052024
      Consensus CDS
      CCDS30161.2
      UniProtKB/TrEMBL
      A2AM37, Q5RKW0
      Related
      ENSMUSP00000115237.2, OTTMUSP00000019219, ENSMUST00000135107.3, OTTMUST00000042794
      Conserved Domains (2) summary
      cd01388
      Location:143214
      SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
      pfam12336
      Location:213306
      SOXp; SOX transcription factor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      60891366..60893430 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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