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    FBXL5 F-box and leucine rich repeat protein 5 [ Bos taurus (cattle) ]

    Gene ID: 519695, updated on 3-Apr-2024

    Summary

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    Official Symbol
    FBXL5provided by VGNC
    Official Full Name
    F-box and leucine rich repeat protein 5provided by VGNC
    Primary source
    VGNC:VGNC:28891
    See related
    BGD:BT21102; Ensembl:ENSBTAG00000021214
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (110760350..110819077, complement)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene coiled-coil and C2 domain containing 2A Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene microRNA mir-2448 Neighboring gene uncharacterized LOC104968939 Neighboring gene family with sequence similarity 200 member B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC148944

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular iron ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    F-box/LRR-repeat protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082440.1 → NP_001075909.1  F-box/LRR-repeat protein 5

      See identical proteins and their annotated locations for NP_001075909.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133613
      UniProtKB/Swiss-Prot
      A2VE78
      Related
      ENSBTAP00000028266.7, ENSBTAT00000028266.7
      Conserved Domains (4) summary
      cd09293
      Location:354 → 408
      AMN1; Antagonist of mitotic exit network protein 1
      cd12109
      Location:7 → 160
      Hr_FBXL5; Hemerythrin-like domain of FBXL5-like proteins
      sd00034
      Location:333 → 357
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:205 → 249
      F-box-like; F-box-like

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      110760350..110819077 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024993214.2 → XP_024848982.1  F-box/LRR-repeat protein 5 isoform X2

      Conserved Domains (4) summary
      cd12109
      Location:1 → 105
      Hr_FBXL5; Hemerythrin-like domain of FBXL5-like proteins
      sd00034
      Location:278 → 302
      LRR_AMN1; leucine-rich repeat [structural motif]
      pfam12937
      Location:150 → 194
      F-box-like; F-box-like
      cl28166
      Location:299 → 353
      AMN1; Antagonist of mitotic exit network protein 1

    2. XM_059887510.1 → XP_059743493.1  F-box/LRR-repeat protein 5 isoform X1

    3. XM_059887511.1 → XP_059743494.1  F-box/LRR-repeat protein 5 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2VE78.1 GenPept UniProtKB/Swiss-Prot:A2VE78

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