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    PLA2G6 phospholipase A2 group VI [ Homo sapiens (human) ]

    Gene ID: 8398, updated on 6-May-2018
    Official Symbol
    PLA2G6provided by HGNC
    Official Full Name
    phospholipase A2 group VIprovided by HGNC
    Primary source
    HGNC:HGNC:9039
    See related
    Ensembl:ENSG00000184381 MIM:603604; Vega:OTTHUMG00000151246
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GVI; PLA2; INAD1; NBIA2; iPLA2; NBIA2A; NBIA2B; PARK14; PNPLA9; CaI-PLA2; IPLA2-VIA; iPLA2beta
    Summary
    The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
    Expression
    Broad expression in testis (RPKM 12.7), gall bladder (RPKM 8.6) and 25 other tissues See more
    Orthologs
    See PLA2G6 in Genome Data Viewer
    Location:
    22q13.1
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 22 NC_000022.11 (38111495..38192100, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (38507502..38577857, complement)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373027 Neighboring gene solute carrier family 16 member 8 Neighboring gene BAI1 associated protein 2 like 2 Neighboring gene MAF bZIP transcription factor F Neighboring gene transmembrane protein 184B Neighboring gene small nucleolar RNA, H/ACA box 92

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    NHGRI GWAS Catalog

    Description
    Biological, clinical and population relevance of 95 loci for blood lipids.
    NHGRI GWA Catalog
    Discovery and refinement of loci associated with lipid levels.
    NHGRI GWA Catalog
    Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.
    NHGRI GWA Catalog
    Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk.
    NHGRI GWA Catalog
    Genome-wide association study identifies three loci associated with melanoma risk.
    NHGRI GWA Catalog
    Genome-wide association study identifies three new melanoma susceptibility loci.
    NHGRI GWA Catalog
    Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi.
    NHGRI GWA Catalog

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope surface glycoprotein gp120 env HIV-1 gp120 causes an activation of phospholipase A2, resulting in the increased release of arachidonic acid, which may sensitize the NMDA receptor PubMed
    env HIV-1 gp120 induces a specific phospholipase A2 (PLA2) activation in lymphocytes through binding to CD4, but this effect is not sufficient to accomplish virus/cell fusion PubMed

    Go to the HIV-1, Human Interaction Database

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    ATP-dependent protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    calcium-independent phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
     
    calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity TAS
    Traceable Author Statement
    more info
     
    phospholipase A2 activity TAS
    Traceable Author Statement
    more info
     
    phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA
    Inferred from Electronic Annotation
    more info
     
    serine hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    Fc-gamma receptor signaling pathway involved in phagocytosis TAS
    Traceable Author Statement
    more info
     
    antibacterial humoral response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cardiolipin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    maternal process involved in female pregnancy IEA
    Inferred from Electronic Annotation
    more info
     
    memory IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylcholine acyl-chain remodeling TAS
    Traceable Author Statement
    more info
     
    phosphatidylethanolamine acyl-chain remodeling TAS
    Traceable Author Statement
    more info
     
    positive regulation of arachidonic acid secretion IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of blood vessel diameter IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of exocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein kinase C signaling IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of release of cytochrome c from mitochondria IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of store-operated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    response to endoplasmic reticulum stress IEA
    Inferred from Electronic Annotation
    more info
     
    urinary bladder smooth muscle contraction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
     
    cytosol TAS
    Traceable Author Statement
    more info
     
    extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule organizing center IDA
    Inferred from Direct Assay
    more info
     
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    85/88 kDa calcium-independent phospholipase A2
    Names
    85 kDa calcium-independent phospholipase A2
    GVI PLA2
    iPLA2-beta
    intracellular membrane-associated calcium-independent phospholipase A2 beta
    neurodegeneration with brain iron accumulation 2
    patatin-like phospholipase domain-containing protein 9
    phospholipase A2, group VI (cytosolic, calcium-independent)
    NP_001004426.1
    NP_001186491.1
    NP_001336793.1
    NP_001336794.1
    NP_001336795.1
    NP_001336796.1
    NP_001336797.1
    NP_001336798.1
    NP_003551.2
    XP_005261821.1
    XP_005261822.1
    XP_006724395.1
    XP_011528724.1
    XP_011528726.1
    XP_011528727.1
    XP_011528728.1
    XP_016884472.1
    XP_016884475.1
    XP_016884476.1
    XP_016884477.1
    XP_024308048.1
    XP_024308049.1
    XP_024308050.1
    XP_024308051.1
    XP_024308052.1
    XP_024308053.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_007094.2 RefSeqGene

      Range
      28937..99196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001004426.2NP_001004426.1  85/88 kDa calcium-independent phospholipase A2 isoform b

      See identical proteins and their annotated locations for NP_001004426.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but lacks an internal segment compared to isoform a. Variants 2, 3, 5 and 6 encode the same isoform (b). Isoform b is found in the cytoplasm while isoform a is membrane-bound.
      Source sequence(s)
      AF064594, BC036742, BC051904, DC376896
      Consensus CDS
      CCDS33645.1
      UniProtKB/Swiss-Prot
      O60733
      Related
      ENSP00000335149.3, ENST00000335539.7
      Conserved Domains (4) summary
      cd07212
      Location:426739
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:214370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:350395
      Ank_4; Ankyrin repeats (many copies)
    2. NM_001199562.2NP_001186491.1  85/88 kDa calcium-independent phospholipase A2 isoform b

      See identical proteins and their annotated locations for NP_001186491.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but lacks an internal segment compared to isoform a. Variants 2, 3, 5 and 6 encode the same protein (isoform b). Isoform b is found in the cytoplasm while isoform a is membrane-bound.
      Source sequence(s)
      AF064594, AK290825, BC051904, DC409316
      Consensus CDS
      CCDS33645.1
      UniProtKB/Swiss-Prot
      O60733
      Related
      ENSP00000386100.1, OTTHUMP00000199457, ENST00000402064.5, OTTHUMT00000321861
      Conserved Domains (4) summary
      cd07212
      Location:426739
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:214370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:350395
      Ank_4; Ankyrin repeats (many copies)
    3. NM_001349864.1NP_001336793.1  85/88 kDa calcium-independent phospholipase A2 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Both variants 1 and 4 encode the same protein (isoform a). Isoform a is membrane-bound while isoform b is found in the cytoplasm.
      Source sequence(s)
      AF064594, BC036742, BC051904, DC376896
      Conserved Domains (3) summary
      cd07212
      Location:480793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
    4. NM_001349865.1NP_001336794.1  85/88 kDa calcium-independent phospholipase A2 isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The resulting isoform (b) has the same N- and C-termini but lacks an internal segment compared to isoform a. Variants 2, 3, 5 and 6 encode the same isoform (b). Isoform b is found in the cytoplasm while isoform a is membrane-bound.
      Source sequence(s)
      AF064594, AK290825, BC051904, DC318003, DC376896
      Conserved Domains (4) summary
      cd07212
      Location:426739
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:214370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:350395
      Ank_4; Ankyrin repeats (many copies)
    5. NM_001349866.1NP_001336795.1  85/88 kDa calcium-independent phospholipase A2 isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The resulting isoform (b) has the same N- and C-termini but lacks an internal segment compared to isoform a. Variants 2, 3, 5 and 6 encode the same isoform (b). Isoform b is found in the cytoplasm while isoform a is membrane-bound.
      Source sequence(s)
      AF064594, BC051904, DC400693, DC409316
      Conserved Domains (4) summary
      cd07212
      Location:426739
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:214370
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:350395
      Ank_4; Ankyrin repeats (many copies)
    6. NM_001349867.1NP_001336796.1  85/88 kDa calcium-independent phospholipase A2 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (7) contains multiple differences in the 5' UTR, one of which results in use of a downstream start codon, compared to variant 1. The resulting isoform (c) has a shorter N-terminus than isoform a.
      Source sequence(s)
      AF064594, AK290825, BC051904, DA290853, DA500195, DC409316
      Conserved Domains (4) summary
      cd07212
      Location:302615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12199
      Ank_2; Ankyrin repeats (3 copies)
    7. NM_001349868.1NP_001336797.1  85/88 kDa calcium-independent phospholipase A2 isoform d

      Status: REVIEWED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR and lacks an exon in the 5' coding region, compared to variant 1. These differences result in use of an alternate start codon, resulting in an isoform (d) with a shorter and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AF064594, BC036742, BC051904, BE278797, DC409316
      Conserved Domains (3) summary
      cd07212
      Location:254567
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:59177
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:6088
      ANK; ANK repeat [structural motif]
    8. NM_001349869.1NP_001336798.1  85/88 kDa calcium-independent phospholipase A2 isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) contains multiple differences in the 5' UTR, one of which results in use of a downstream start codon, and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The resulting isoform (e) has a shorter N-terminus and lacks an internal segment compared to isoform a.
      Source sequence(s)
      AF064594, AK290825, BC051904, BP251849, DA290853, DC409316
      Conserved Domains (4) summary
      cd07212
      Location:248561
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:36192
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:172217
      Ank_4; Ankyrin repeats (many copies)
    9. NM_003560.3NP_003551.2  85/88 kDa calcium-independent phospholipase A2 isoform a

      See identical proteins and their annotated locations for NP_003551.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Both variants 1 and 4 encode the same protein (isoform a). Isoform a is membrane-bound while isoform b is found in the cytoplasm.
      Source sequence(s)
      AF064594, BC036742, BC051904, DC376896
      Consensus CDS
      CCDS13967.1
      UniProtKB/Swiss-Prot
      O60733
      Related
      ENSP00000333142.3, OTTHUMP00000199456, ENST00000332509.7, OTTHUMT00000321860
      Conserved Domains (3) summary
      cd07212
      Location:480793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p12 Primary Assembly

      Range
      38111495..38192100 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006724332.4XP_006724395.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

      See identical proteins and their annotated locations for XP_006724395.1

      UniProtKB/Swiss-Prot
      O60733
      Conserved Domains (3) summary
      cd07212
      Location:480793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
    2. XM_005261765.2XP_005261822.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

      See identical proteins and their annotated locations for XP_005261822.1

      UniProtKB/Swiss-Prot
      O60733
      Conserved Domains (3) summary
      cd07212
      Location:480793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
    3. XM_024452283.1XP_024308051.1  85/88 kDa calcium-independent phospholipase A2 isoform X5

      Conserved Domains (3) summary
      cd07212
      Location:254567
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:59177
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:6088
      ANK; ANK repeat [structural motif]
    4. XM_005261764.3XP_005261821.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

      See identical proteins and their annotated locations for XP_005261821.1

      UniProtKB/Swiss-Prot
      O60733
      Conserved Domains (3) summary
      cd07212
      Location:480793
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:285403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
    5. XM_011530422.1XP_011528724.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      Conserved Domains (4) summary
      cd07212
      Location:445758
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:250368
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:256345
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:251279
      ANK; ANK repeat [structural motif]
    6. XM_017028983.1XP_016884472.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

      Conserved Domains (4) summary
      cd07212
      Location:248561
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:36192
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:172217
      Ank_4; Ankyrin repeats (many copies)
    7. XM_011530424.1XP_011528726.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

      See identical proteins and their annotated locations for XP_011528726.1

      Conserved Domains (4) summary
      cd07212
      Location:302615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12199
      Ank_2; Ankyrin repeats (3 copies)
    8. XM_024452285.1XP_024308053.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

      Conserved Domains (4) summary
      cd07212
      Location:248561
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:36192
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:172217
      Ank_4; Ankyrin repeats (many copies)
    9. XM_024452281.1XP_024308049.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

      Conserved Domains (4) summary
      cd07212
      Location:302615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12199
      Ank_2; Ankyrin repeats (3 copies)
    10. XM_024452284.1XP_024308052.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

      Conserved Domains (4) summary
      cd07212
      Location:248561
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:36192
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:172217
      Ank_4; Ankyrin repeats (many copies)
    11. XM_024452280.1XP_024308048.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

      Conserved Domains (4) summary
      cd07212
      Location:302615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12199
      Ank_2; Ankyrin repeats (3 copies)
    12. XM_024452282.1XP_024308050.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

      Conserved Domains (4) summary
      cd07212
      Location:302615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12199
      Ank_2; Ankyrin repeats (3 copies)
    13. XM_011530425.1XP_011528727.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

      See identical proteins and their annotated locations for XP_011528727.1

      Conserved Domains (4) summary
      cd07212
      Location:302615
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:107225
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:108136
      ANK; ANK repeat [structural motif]
      cl26073
      Location:12199
      Ank_2; Ankyrin repeats (3 copies)
    14. XM_017028986.2XP_016884475.1  85/88 kDa calcium-independent phospholipase A2 isoform X7

    15. XM_011530426.3XP_011528728.1  85/88 kDa calcium-independent phospholipase A2 isoform X4

      Conserved Domains (4) summary
      cd00204
      Location:285403
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:291380
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:286314
      ANK; ANK repeat [structural motif]
      cl11396
      Location:480584
      Patatin_and_cPLA2; Patatins and Phospholipases
    16. XM_017028988.2XP_016884477.1  85/88 kDa calcium-independent phospholipase A2 isoform X9

      UniProtKB/Swiss-Prot
      O60733
    17. XM_017028987.2XP_016884476.1  85/88 kDa calcium-independent phospholipase A2 isoform X8

    RNA

    1. XR_001755325.2 RNA Sequence

    2. XR_001755327.2 RNA Sequence

    3. XR_001755328.2 RNA Sequence

    4. XR_244390.3 RNA Sequence

    5. XR_937938.3 RNA Sequence

    6. XR_937939.3 RNA Sequence

    7. XR_937940.3 RNA Sequence

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