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    csrB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847719, updated on 14-Apr-2023

    Summary

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    Gene symbol
    csrB
    Primary source
    ASAP:ABE-0047213
    Locus tag
    b4408
    See related
    ECOCYC:G0-8785
    Gene type
    ncRNA
    RNA name
    other
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2787
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    Genomic context

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    Sequence:
    NC_000913.3 (2924156..2924524, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative flavodoxin YqcA Neighboring gene tRNA pseudouridine(65) synthase Neighboring gene DUF446 domain-containing protein YqcC Neighboring gene SecY-interacting protein Neighboring gene 7-cyano-7-deazaguanine reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CsrD evolution was driven by the selective advantage of decoupling Csr small RNA decay from CsrA binding, connecting it instead to the availability of a preferred carbon source.
      Title: Antagonistic control of the turnover pathway for the global regulatory sRNA CsrB by the CsrA and CsrD proteins.
    2. CsrA binds to the regulatory small RNAs (sRNAs) CsrB and CsrC, which antagonize its activity.
      Title: Circuitry Linking the Catabolite Repression and Csr Global Regulatory Systems of Escherichia coli.
    3. Data indicate that CsrA proteins are sequestered by CsrB noncoding RNAs, and the degradation of CsrB RNAs is increased by CsrD proteins.
      Title: Rapid and robust signaling in the CsrA cascade via RNA-protein interactions and feedback regulation.
    4. CsrA and DksA are both necessary for full expression of csrB and csrC.
      Title: Circuitry linking the Csr and stringent response global regulatory systems.
    5. The expression of the CsrB and and CsrC is controlled by the amino acid availability in the growth medium.
      Title: The Escherichia coli CsrB and CsrC small RNAs are strongly induced during growth in nutrient-poor medium.
    Submit: New GeneRIF Correction

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