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    METTL7A methyltransferase like 7A [ Homo sapiens (human) ]

    Gene ID: 25840, updated on 19-May-2018
    Official Symbol
    METTL7Aprovided by HGNC
    Official Full Name
    methyltransferase like 7Aprovided by HGNC
    Primary source
    See related
    Ensembl:ENSG00000185432 Vega:OTTHUMG00000169484
    Gene type
    protein coding
    RefSeq status
    Homo sapiens
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Broad expression in liver (RPKM 132.2), thyroid (RPKM 109.3) and 24 other tissues See more
    See METTL7A in Genome Data Viewer
    Exon count:
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 12 NC_000012.12 (50924751..50932517)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (51317780..51326300)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 519, pseudogene Neighboring gene transmembrane serine protease 12 Neighboring gene HIG1 hypoxia inducible domain family member 1C Neighboring gene solute carrier family 11 member 2 Neighboring gene RNA, U7 small nuclear 39 pseudogene

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016
    • Immune System, organism-specific biosystem (from REACTOME)
      Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
    • Innate Immune System, organism-specific biosystem (from REACTOME)
      Innate Immune System, organism-specific biosystemInnate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup
    • Neutrophil degranulation, organism-specific biosystem (from REACTOME)
      Neutrophil degranulation, organism-specific biosystemNeutrophils are the most abundant leukocytes (white blood cells), indispensable in defending the body against invading microorganisms. In response to infection, neutrophils leave the circulation and ...
    Products Interactant Other Gene Complex Source Pubs Description



    Clone Names

    • DKFZp586A0522

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    Process Evidence Code Pubs
    methylation IEA
    Inferred from Electronic Annotation
    more info
    neutrophil degranulation TAS
    Traceable Author Statement
    more info
    Component Evidence Code Pubs
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    extracellular region TAS
    Traceable Author Statement
    more info
    lipid droplet IDA
    Inferred from Direct Assay
    more info
    membrane IEA
    Inferred from Electronic Annotation
    more info
    tertiary granule lumen TAS
    Traceable Author Statement
    more info
    Preferred Names
    methyltransferase-like protein 7A
    protein AAM-B

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_014033.3NP_054752.3  methyltransferase-like protein 7A precursor

      See identical proteins and their annotated locations for NP_054752.3

      Status: VALIDATED

      Source sequence(s)
      AC008121, AY358797, BM805242
      Consensus CDS
      ENSP00000331787.4, ENST00000332160.4
      Conserved Domains (1) summary
      Methyltransf_11; Methyltransferase domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly


    1. NC_000012.12 Reference GRCh38.p12 Primary Assembly

      GenBank, FASTA, Sequence Viewer (Graphics)
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