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    CALD1 caldesmon 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 281660, updated on 30-Jan-2025

    Summary

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    Official Symbol
    CALD1provided by VGNC
    Official Full Name
    caldesmon 1provided by VGNC
    Primary source
    VGNC:VGNC:26706
    See related
    BGD:BT27319; EnsemblRapid:ENSBTAG00070025359
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CALD1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (98449568..98681120)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene aldo-keto reductase family 1 member B10 Neighboring gene bisphosphoglycerate mutase Neighboring gene uncharacterized LOC104972216 Neighboring gene AGBL carboxypeptidase 3 Neighboring gene U6 spliceosomal RNA Neighboring gene transmembrane protein 140 Neighboring gene cell cycle regulator of NHEJ

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Identification of multiple genes in bovine retinal pericytes altered by exposure to elevated levels of glucose by using mRNA differential display. Aiello LP, et al. Proc Natl Acad Sci U S A, 1994 Jun 21. PMID 8016144, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables myosin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    non-muscle caldesmon
    Names
    CDM
    L-caldesmon
    caldesmon, smooth muscle

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174258.2 → NP_776683.1  non-muscle caldesmon

      Status: PROVISIONAL

      Source sequence(s)
      AY154474
      UniProtKB/TrEMBL
      F1MLW0, Q8HYY3
      Related
      ENSBTAP00070034224.1, ENSBTAT00070057430.1
      Conserved Domains (1) summary
      pfam02029
      Location:260 → 522
      Caldesmon; Caldesmon

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      98449568..98681120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024990452.1 → XP_024846220.1  non-muscle caldesmon isoform X1

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Conserved Domains (2) summary
      pfam02029
      Location:517 → 776
      Caldesmon
      cl26511
      Location:147 → 629
      Neuromodulin_N; Gap junction protein N-terminal region

    2. XM_024990454.1 → XP_024846222.1  non-muscle caldesmon isoform X1

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Conserved Domains (2) summary
      pfam02029
      Location:517 → 776
      Caldesmon
      cl26511
      Location:147 → 629
      Neuromodulin_N; Gap junction protein N-terminal region

    3. XM_024990451.2 → XP_024846219.1  non-muscle caldesmon isoform X1

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Conserved Domains (2) summary
      pfam02029
      Location:517 → 776
      Caldesmon
      cl26511
      Location:147 → 629
      Neuromodulin_N; Gap junction protein N-terminal region

    4. XM_024990450.2 → XP_024846218.1  non-muscle caldesmon isoform X1

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Conserved Domains (2) summary
      pfam02029
      Location:517 → 776
      Caldesmon
      cl26511
      Location:147 → 629
      Neuromodulin_N; Gap junction protein N-terminal region

    5. XM_005205755.5 → XP_005205812.1  non-muscle caldesmon isoform X2

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Related
      ENSBTAP00070034301.1, ENSBTAT00070057595.1
      Conserved Domains (1) summary
      pfam02029
      Location:514 → 776
      Caldesmon; Caldesmon

    6. XM_024990458.2 → XP_024846226.1  non-muscle caldesmon isoform X5

      UniProtKB/TrEMBL
      F1MLW0
      Conserved Domains (1) summary
      pfam02029
      Location:263 → 522
      Caldesmon

    7. XM_005205759.5 → XP_005205816.1  non-muscle caldesmon isoform X6

      UniProtKB/TrEMBL
      F1MLW0
      Related
      ENSBTAP00070034272.1, ENSBTAT00070057532.1
      Conserved Domains (1) summary
      pfam02029
      Location:260 → 522
      Caldesmon; Caldesmon

    8. XM_024990455.2 → XP_024846223.1  non-muscle caldesmon isoform X1

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Conserved Domains (2) summary
      pfam02029
      Location:517 → 776
      Caldesmon
      cl26511
      Location:147 → 629
      Neuromodulin_N; Gap junction protein N-terminal region

    9. XM_059885401.1 → XP_059741384.1  non-muscle caldesmon isoform X4

      UniProtKB/TrEMBL
      A0AAA9TRW0

    10. XM_024990456.2 → XP_024846224.1  non-muscle caldesmon isoform X1

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Conserved Domains (2) summary
      pfam02029
      Location:517 → 776
      Caldesmon
      cl26511
      Location:147 → 629
      Neuromodulin_N; Gap junction protein N-terminal region

    11. XM_024990459.2 → XP_024846227.1  non-muscle caldesmon isoform X5

      UniProtKB/TrEMBL
      F1MLW0
      Conserved Domains (1) summary
      pfam02029
      Location:263 → 522
      Caldesmon

    12. XM_010804515.3 → XP_010802817.1  non-muscle caldesmon isoform X6

      UniProtKB/TrEMBL
      F1MLW0
      Conserved Domains (1) summary
      pfam02029
      Location:260 → 522
      Caldesmon; Caldesmon

    13. XM_024990457.2 → XP_024846225.1  non-muscle caldesmon isoform X3

      UniProtKB/TrEMBL
      A0AAA9TRW0
      Conserved Domains (2) summary
      pfam02029
      Location:511 → 770
      Caldesmon
      cl26511
      Location:141 → 623
      Neuromodulin_N; Gap junction protein N-terminal region

    14. XM_024990460.2 → XP_024846228.1  non-muscle caldesmon isoform X7

      UniProtKB/TrEMBL
      F1MLW0
      Conserved Domains (1) summary
      pfam02029
      Location:257 → 516
      Caldesmon

    15. XM_010804516.2 → XP_010802818.1  non-muscle caldesmon isoform X8

      UniProtKB/TrEMBL
      F1MLW0
      Related
      ENSBTAP00070034243.1, ENSBTAT00070057471.1
      Conserved Domains (1) summary
      pfam02029
      Location:254 → 516
      Caldesmon; Caldesmon
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q27976.1 GenPept UniProtKB/Swiss-Prot:Q27976

    Gene LinkOut

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