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    lys3 saccharopine dehydrogenase Lys3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541500, updated on 15-Mar-2024

    Summary

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    Gene symbol
    lys3
    Gene description
    saccharopine dehydrogenase Lys3
    Primary source
    PomBase:SPAC227.18
    Locus tag
    SPAC227.18
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC2F7.01
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    Genomic context

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    See lys3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (530261..531981)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative protein phosphatase regulatory subunit Reg1 Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene GINS complex subunit Psf3 Neighboring gene putative NLI-interacting factor-like phosphatase family protein Neighboring gene DYRK family protein kinase Pom1 Neighboring gene mediator complex subunit Pmc2/Med1 Neighboring gene eukaryotic translation initiation factor 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lysine biosynthesis pathway and biochemical blocks of lysine auxotrophs of Schizosaccharomyces pombe. Ye ZH, et al. J Bacteriol, 1988 Dec. PMID 3142867, Free PMC Article
    2. A genetic engineering solution to the "arginine conversion problem" in stable isotope labeling by amino acids in cell culture (SILAC). Bicho CC, et al. Mol Cell Proteomics, 2010 Jul. PMID 20460254, Free PMC Article
    3. Fission yeast autophagy induced by nitrogen starvation generates a nitrogen source that drives adaptation processes. Kohda TA, et al. Genes Cells, 2007 Feb. PMID 17295836
    4. Six new amino acid-auxotrophic markers for targeted gene integration and disruption in fission yeast. Ma Y, et al. Curr Genet, 2007 Aug. PMID 17622533
    5. A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast. Paul SK, et al. FEBS J, 2009 Sep. PMID 19682301

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables saccharopine dehydrogenase (NAD+, L-lysine-forming) activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables saccharopine dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lysine biosynthetic process via aminoadipic acid IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in lysine biosynthetic process via aminoadipic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    saccharopine dehydrogenase Lys3
    NP_592972.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      530261..531981
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018372.2 → NP_592972.1  saccharopine dehydrogenase Lys3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_592972.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09694, Q9UTC1
      Conserved Domains (1) summary
      cd12188
      Location:4 → 366
      SDH; Saccharopine Dehydrogenase NAD-binding and catalytic domains
    Nucleotide Protein
    Heading Accession and Version

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