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    Vps35 VPS35 retromer complex component [ Mus musculus (house mouse) ]

    Gene ID: 65114, updated on 4-Sep-2016
    Official Symbol
    Vps35provided by MGI
    Official Full Name
    VPS35 retromer complex componentprovided by MGI
    Primary source
    MGI:MGI:1890467
    See related
    Ensembl:ENSMUSG00000031696 Vega:OTTMUSG00000061416
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mem3; AI647796
    Orthologs
    Location:
    8 C3; 8 41.61 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (85260392..85299497, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (87784291..87823396, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene CDC28 protein kinase 1b, retrogene Neighboring gene predicted gene, 33296 Neighboring gene zinc finger protein 46 pseudogene Neighboring gene olfactory receptor 371 Neighboring gene origin recognition complex, subunit 6 Neighboring gene myosin light chain kinase 3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    negative regulation of late endosome to lysosome transport ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of Wnt protein secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of canonical Wnt signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of protein stability ISO
    Inferred from Sequence Orthology
    more info
     
    retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    retrograde transport, endosome to Golgi ISO
    Inferred from Sequence Orthology
    more info
     
    retrograde transport, endosome to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    transcytosis ISO
    Inferred from Sequence Orthology
    more info
     
    transport IEA
    Inferred from Electronic Annotation
    more info
     
    vacuolar protein processing ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    early endosome ISO
    Inferred from Sequence Orthology
    more info
     
    endosome ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic density IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retromer complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retromer complex ISO
    Inferred from Sequence Orthology
    more info
     
    tubular endosome ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    vacuolar protein sorting-associated protein 35
    Names
    maternal embryonic message 3
    maternal-embryonic 3
    vacuolar protein sorting 35
    vesicle protein sorting 35

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022997.4NP_075373.1  vacuolar protein sorting-associated protein 35

      See identical proteins and their annotated locations for NP_075373.1

      Status: PROVISIONAL

      Source sequence(s)
      AC134854, AC159275
      Consensus CDS
      CCDS40421.1
      UniProtKB/Swiss-Prot
      Q9EQH3
      UniProtKB/TrEMBL
      Q3TRJ1
      Related
      ENSMUSP00000034131, OTTMUSP00000077724, ENSMUST00000034131, OTTMUST00000149866
      Conserved Domains (1) summary
      pfam03635
      Location:15752
      Vps35; Vacuolar protein sorting-associated protein 35

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      85260392..85299497 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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