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    Kif20b kinesin family member 20B [ Mus musculus (house mouse) ]

    Gene ID: 240641, updated on 4-Jun-2017
    Official Symbol
    Kif20bprovided by MGI
    Official Full Name
    kinesin family member 20Bprovided by MGI
    Primary source
    MGI:MGI:2444576
    See related
    Ensembl:ENSMUSG00000024795
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    33cex; magoo; Mphosph1; B130024C23; C330014J10Rik
    Orthologs
    Location:
    19; 19 C1
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (34922341..34975750)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (34996848..35050221)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 16 (monocarboxylic acid transporters), member 12 Neighboring gene predicted gene, 18425 Neighboring gene pantothenate kinase 1 Neighboring gene microRNA 107 Neighboring gene microRNA 1950 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 5 pseudogene Neighboring gene predicted gene, 31568

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATP-dependent microtubule motor activity, plus-end-directed ISO
    Inferred from Sequence Orthology
    more info
     
    ATPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    WW domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    neural tube closure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuron projection morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of intracellular protein transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of mitotic cytokinetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein localization to microtubule IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of establishment of cell polarity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of establishment of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of establishment of protein localization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of mitotic nuclear division IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of neuron migration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    contractile ring ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    midbody IDA
    Inferred from Direct Assay
    more info
    PubMed 
    midbody ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle midzone ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spindle midzone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    kinesin-like protein KIF20B
    Names
    M-phase phosphoprotein 1
    MPP1
    N-6 kinesin
    kinesin-related motor interacting with PIN1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183046.1NP_898867.1  kinesin-like protein KIF20B

      See identical proteins and their annotated locations for NP_898867.1

      Status: VALIDATED

      Source sequence(s)
      AK045067, AK135856, AK143629, AK145779, AY259532
      Consensus CDS
      CCDS37967.1
      UniProtKB/Swiss-Prot
      Q80WE4
      Related
      ENSMUSP00000084599.5, ENSMUST00000087341.5
      Conserved Domains (6) summary
      COG1340
      Location:10411319
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:64477
      Kinesin; Kinesin motor domain
      pfam00261
      Location:12501478
      Tropomyosin; Tropomyosin
      pfam10211
      Location:12281301
      Ax_dynein_light; Axonemal dynein light chain
      cl23887
      Location:11791331
      DUF4349; Domain of unknown function (DUF4349)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      34922341..34975750
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527082.3XP_006527145.1  kinesin-like protein KIF20B isoform X2

      Conserved Domains (6) summary
      COG1340
      Location:10411319
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:64477
      Kinesin; Kinesin motor domain
      pfam00261
      Location:12501478
      Tropomyosin; Tropomyosin
      pfam10211
      Location:12281301
      Ax_dynein_light; Axonemal dynein light chain
      cl23887
      Location:11791331
      DUF4349; Domain of unknown function (DUF4349)
    2. XM_006527083.3XP_006527146.1  kinesin-like protein KIF20B isoform X3

      See identical proteins and their annotated locations for XP_006527146.1

      UniProtKB/TrEMBL
      B7ZWN1
      Conserved Domains (6) summary
      COG1340
      Location:10011279
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:64477
      Kinesin; Kinesin motor domain
      pfam00261
      Location:12101438
      Tropomyosin; Tropomyosin
      pfam10211
      Location:11881261
      Ax_dynein_light; Axonemal dynein light chain
      cl23887
      Location:11391291
      DUF4349; Domain of unknown function (DUF4349)
    3. XM_011247247.2XP_011245549.1  kinesin-like protein KIF20B isoform X4

      Conserved Domains (4) summary
      COG1340
      Location:10411319
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:64477
      Kinesin; Kinesin motor domain
      cl23887
      Location:11791331
      DUF4349; Domain of unknown function (DUF4349)
    4. XM_006527084.3XP_006527147.1  kinesin-like protein KIF20B isoform X5

      See identical proteins and their annotated locations for XP_006527147.1

      Conserved Domains (3) summary
      COG1340
      Location:655933
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cl22853
      Location:189
      Motor_domain; Myosin and Kinesin motor domain
      pfam10211
      Location:842915
      Ax_dynein_light; Axonemal dynein light chain
    5. XM_006527080.2XP_006527143.1  kinesin-like protein KIF20B isoform X1

      See identical proteins and their annotated locations for XP_006527143.1

      UniProtKB/Swiss-Prot
      Q80WE4
      Conserved Domains (6) summary
      COG1340
      Location:10411319
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:64477
      Kinesin; Kinesin motor domain
      pfam00261
      Location:12501478
      Tropomyosin; Tropomyosin
      pfam10211
      Location:12281301
      Ax_dynein_light; Axonemal dynein light chain
      cl23887
      Location:11791331
      DUF4349; Domain of unknown function (DUF4349)
    6. XM_006527081.2XP_006527144.1  kinesin-like protein KIF20B isoform X1

      See identical proteins and their annotated locations for XP_006527144.1

      UniProtKB/Swiss-Prot
      Q80WE4
      Conserved Domains (6) summary
      COG1340
      Location:10411319
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      pfam00225
      Location:64477
      Kinesin; Kinesin motor domain
      pfam00261
      Location:12501478
      Tropomyosin; Tropomyosin
      pfam10211
      Location:12281301
      Ax_dynein_light; Axonemal dynein light chain
      cl23887
      Location:11791331
      DUF4349; Domain of unknown function (DUF4349)
    7. XM_006527085.2XP_006527148.1  kinesin-like protein KIF20B isoform X5

      See identical proteins and their annotated locations for XP_006527148.1

      Conserved Domains (3) summary
      COG1340
      Location:655933
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cl22853
      Location:189
      Motor_domain; Myosin and Kinesin motor domain
      pfam10211
      Location:842915
      Ax_dynein_light; Axonemal dynein light chain
    8. XM_006527086.2XP_006527149.1  kinesin-like protein KIF20B isoform X6

      UniProtKB/Swiss-Prot
      Q80WE4
      Conserved Domains (3) summary
      COG1340
      Location:615893
      COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
      cl22853
      Location:189
      Motor_domain; Myosin and Kinesin motor domain
      pfam10211
      Location:802875
      Ax_dynein_light; Axonemal dynein light chain
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