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    PLA2G16 phospholipase A2 group XVI [ Homo sapiens (human) ]

    Gene ID: 11145, updated on 17-Sep-2016
    Official Symbol
    PLA2G16provided by HGNC
    Official Full Name
    phospholipase A2 group XVIprovided by HGNC
    Primary source
    HGNC:HGNC:17825
    See related
    Ensembl:ENSG00000176485 HPRD:13671; MIM:613867; Vega:OTTHUMG00000167852
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AdPLA; HRSL3; HRASLS3; HREV107; HREV107-1; HREV107-3; H-REV107-1
    Orthologs
    Location:
    11q12.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 11 NC_000011.10 (63574462..63616926, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (63341934..63381941, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene retinoic acid receptor responder 3 Neighboring gene HRAS like suppressor 2 Neighboring gene uncharacterized LOC105369335 Neighboring gene uncharacterized LOC107984336 Neighboring gene inner mitochondrial membrane peptidase subunit 1 pseudogene 1 Neighboring gene atlastin GTPase 3 Neighboring gene reticulon 3

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC118754

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    1-acyl-2-lysophosphatidylserine acylhydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylcholine 1-acylhydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylserine 1-acylhydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipase A2 activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phospholipase A2 activity TAS
    Traceable Author Statement
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylcholine acyl-chain remodeling TAS
    Traceable Author Statement
    more info
     
    phosphatidylethanolamine acyl-chain remodeling TAS
    Traceable Author Statement
    more info
     
    phosphatidylinositol acyl-chain remodeling TAS
    Traceable Author Statement
    more info
     
    phosphatidylserine acyl-chain remodeling TAS
    Traceable Author Statement
    more info
     
    phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipid metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     
    cytosol TAS
    Traceable Author Statement
    more info
     
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    HRAS-like suppressor 3
    Names
    Ca-independent phospholipase A1/2
    H-rev 107 protein homolog
    HRAS-like suppressor 1
    adipose-specific PLA2
    adipose-specific phospholipase A2
    group XVI phospholipase A1/A2
    group XVI phospholipase A2
    renal carcinoma antigen NY-REN-65
    NP_001121675.1
    NP_009000.2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128203.1NP_001121675.1  HRAS-like suppressor 3

      See identical proteins and their annotated locations for NP_001121675.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform.
      Source sequence(s)
      AI374456, AI590735, BG719903, CK003948
      Consensus CDS
      CCDS8047.1
      UniProtKB/Swiss-Prot
      P53816
      UniProtKB/TrEMBL
      A0A024R561
      Related
      ENSP00000389124, ENST00000415826
      Conserved Domains (2) summary
      pfam04970
      Location:19125
      LRAT; Lecithin retinol acyltransferase
      cl21534
      Location:135
      NLPC_P60; NlpC/P60 family
    2. NM_007069.3NP_009000.2  HRAS-like suppressor 3

      See identical proteins and their annotated locations for NP_009000.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same isoform.
      Source sequence(s)
      AI374456, AI590735, AK313075, AU099540
      Consensus CDS
      CCDS8047.1
      UniProtKB/Swiss-Prot
      P53816
      UniProtKB/TrEMBL
      A0A024R561
      Related
      ENSP00000320337, OTTHUMP00000237069, ENST00000323646, OTTHUMT00000396632
      Conserved Domains (2) summary
      pfam04970
      Location:19125
      LRAT; Lecithin retinol acyltransferase
      cl21534
      Location:135
      NLPC_P60; NlpC/P60 family

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p7 Primary Assembly

      Range
      63574462..63616926 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011544741.1XP_011543043.1  

      See identical proteins and their annotated locations for XP_011543043.1

      Conserved Domains (1) summary
      pfam04970
      Location:34140
      LRAT; Lecithin retinol acyltransferase
    2. XM_006718426.1XP_006718489.1  

      See identical proteins and their annotated locations for XP_006718489.1

      UniProtKB/Swiss-Prot
      P53816
      UniProtKB/TrEMBL
      A0A024R561
      Conserved Domains (2) summary
      pfam04970
      Location:19125
      LRAT; Lecithin retinol acyltransferase
      cl21534
      Location:135
      NLPC_P60; NlpC/P60 family

    Alternate CHM1_1.1

    Genomic

    1. NC_018922.2 Alternate CHM1_1.1

      Range
      63224977..63264973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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