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    P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 [ Mus musculus (house mouse) ]

    Gene ID: 233571, updated on 26-Apr-2018
    Official Symbol
    P2ry6provided by MGI
    Official Full Name
    pyrimidinergic receptor P2Y, G-protein coupled, 6provided by MGI
    Primary source
    MGI:MGI:2673874
    See related
    Ensembl:ENSMUSG00000048779 Vega:OTTMUSG00000060006
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P2Y6; 2010204J23Rik
    Expression
    Broad expression in colon adult (RPKM 37.0), lung adult (RPKM 23.5) and 16 other tissues See more
    Orthologs
    See P2ry6 in Genome Data Viewer
    Location:
    7; 7 E2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (100937630..100975497, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (108086148..108112880, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene RELT tumor necrosis factor receptor Neighboring gene Rho guanine nucleotide exchange factor (GEF) 17 Neighboring gene microRNA 3102 Neighboring gene purinergic receptor P2Y, G-protein coupled 2 Neighboring gene ribosomal protein S29 pseudogene

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled purinergic nucleotide receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    G-protein coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    UDP-activated nucleotide receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pyrimidine nucleotide binding IC
    Inferred by Curator
    more info
    PubMed 
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to organic cyclic compound IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to prostaglandin E stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of smooth muscle cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    transepithelial chloride transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183168.2NP_898991.1  P2Y purinoceptor 6

      See identical proteins and their annotated locations for NP_898991.1

      Status: VALIDATED

      Source sequence(s)
      AC151414
      Consensus CDS
      CCDS21507.1
      UniProtKB/Swiss-Prot
      Q9ERK9
      UniProtKB/TrEMBL
      Q3UQ86
      Related
      ENSMUSP00000055697.4, OTTMUSP00000076426, ENSMUST00000060174.5, OTTMUST00000146916
      Conserved Domains (1) summary
      pfam00001
      Location:44300
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      100937630..100975497 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011241739.2XP_011240041.1  P2Y purinoceptor 6 isoform X1

      See identical proteins and their annotated locations for XP_011240041.1

      UniProtKB/Swiss-Prot
      Q9ERK9
      UniProtKB/TrEMBL
      Q3UQ86
      Conserved Domains (1) summary
      pfam00001
      Location:44300
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    2. XM_006507640.3XP_006507703.1  P2Y purinoceptor 6 isoform X1

      See identical proteins and their annotated locations for XP_006507703.1

      UniProtKB/Swiss-Prot
      Q9ERK9
      UniProtKB/TrEMBL
      Q3UQ86
      Conserved Domains (1) summary
      pfam00001
      Location:44300
      7tm_1; 7 transmembrane receptor (rhodopsin family)
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