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    KBTBD11 kelch repeat and BTB domain containing 11 [ Homo sapiens (human) ]

    Gene ID: 9920, updated on 22-Apr-2017
    Official Symbol
    KBTBD11provided by HGNC
    Official Full Name
    kelch repeat and BTB domain containing 11provided by HGNC
    Primary source
    HGNC:HGNC:29104
    See related
    Ensembl:ENSG00000176595 Vega:OTTHUMG00000163629
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    KLHDC7C
    Orthologs
    Location:
    8p23.3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 8 NC_000008.11 (1970718..2006943)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (1921949..1955109)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 10 Neighboring gene microRNA 596 Neighboring gene uncharacterized LOC100131395 Neighboring gene uncharacterized LOC101928058 Neighboring gene KBTBD11 overlapping transcript 1 Neighboring gene myomesin 2 Neighboring gene microRNA 7160 Neighboring gene uncharacterized LOC105377781

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    NHGRI GWAS Catalog

    Description
    Genome-wide association study of selenium concentrations.
    NHGRI GWA Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    NHGRI GWA Catalog

    Markers

    Homology

    Clone Names

    • KIAA0711

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Cul3-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Preferred Names
    kelch repeat and BTB domain-containing protein 11
    Names
    chronic myelogenous leukemia-associated protein
    kelch domain-containing protein 7B
    kelch repeat and BTB (POZ) domain containing 11

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_014867.2NP_055682.1  kelch repeat and BTB domain-containing protein 11

      See identical proteins and their annotated locations for NP_055682.1

      Status: VALIDATED

      Source sequence(s)
      AB018254, AC019257
      Consensus CDS
      CCDS34795.1
      UniProtKB/Swiss-Prot
      O94819
      Related
      ENSP00000321544.3, OTTHUMP00000224482, ENST00000320248.3, OTTHUMT00000374601
      Conserved Domains (6) summary
      smart00612
      Location:413449
      Kelch; Kelch domain
      smart00225
      Location:141226
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:350398
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:141225
      BTB; BTB/POZ domain
      pfam01344
      Location:348399
      Kelch_1; Kelch motif
      pfam05334
      Location:54136
      DUF719; Protein of unknown function (DUF719)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p7 Primary Assembly

      Range
      1970718..2006943
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011534771.2XP_011533073.1  kelch repeat and BTB domain-containing protein 11 isoform X1

      See identical proteins and their annotated locations for XP_011533073.1

      UniProtKB/Swiss-Prot
      O94819
      Conserved Domains (6) summary
      smart00612
      Location:413449
      Kelch; Kelch domain
      smart00225
      Location:141226
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:350398
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:141225
      BTB; BTB/POZ domain
      pfam01344
      Location:348399
      Kelch_1; Kelch motif
      pfam05334
      Location:54136
      DUF719; Protein of unknown function (DUF719)
    2. XM_011534772.2XP_011533074.1  kelch repeat and BTB domain-containing protein 11 isoform X1

      See identical proteins and their annotated locations for XP_011533074.1

      UniProtKB/Swiss-Prot
      O94819
      Conserved Domains (6) summary
      smart00612
      Location:413449
      Kelch; Kelch domain
      smart00225
      Location:141226
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:350398
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:141225
      BTB; BTB/POZ domain
      pfam01344
      Location:348399
      Kelch_1; Kelch motif
      pfam05334
      Location:54136
      DUF719; Protein of unknown function (DUF719)
    3. XM_017014116.1XP_016869605.1  kelch repeat and BTB domain-containing protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O94819
      Conserved Domains (6) summary
      smart00612
      Location:413449
      Kelch; Kelch domain
      smart00225
      Location:141226
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:350398
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:141225
      BTB; BTB/POZ domain
      pfam01344
      Location:348399
      Kelch_1; Kelch motif
      pfam05334
      Location:54136
      DUF719; Protein of unknown function (DUF719)
    4. XM_017014114.1XP_016869603.1  kelch repeat and BTB domain-containing protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O94819
      Conserved Domains (6) summary
      smart00612
      Location:413449
      Kelch; Kelch domain
      smart00225
      Location:141226
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:350398
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:141225
      BTB; BTB/POZ domain
      pfam01344
      Location:348399
      Kelch_1; Kelch motif
      pfam05334
      Location:54136
      DUF719; Protein of unknown function (DUF719)
    5. XM_017014115.1XP_016869604.1  kelch repeat and BTB domain-containing protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O94819
      Conserved Domains (6) summary
      smart00612
      Location:413449
      Kelch; Kelch domain
      smart00225
      Location:141226
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:350398
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:141225
      BTB; BTB/POZ domain
      pfam01344
      Location:348399
      Kelch_1; Kelch motif
      pfam05334
      Location:54136
      DUF719; Protein of unknown function (DUF719)
    6. XM_017014117.1XP_016869606.1  kelch repeat and BTB domain-containing protein 11 isoform X1

      UniProtKB/Swiss-Prot
      O94819
      Conserved Domains (6) summary
      smart00612
      Location:413449
      Kelch; Kelch domain
      smart00225
      Location:141226
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00038
      Location:350398
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:141225
      BTB; BTB/POZ domain
      pfam01344
      Location:348399
      Kelch_1; Kelch motif
      pfam05334
      Location:54136
      DUF719; Protein of unknown function (DUF719)

    Reference GRCh38.p7 ALT_REF_LOCI_1

    Genomic

    1. NT_187576.1 Reference GRCh38.p7 ALT_REF_LOCI_1

      Range
      157254..190319
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1

    Genomic

    1. NC_018919.2 Alternate CHM1_1.1

      Range
      1921731..1954791
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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