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    Chkb choline kinase beta [ Mus musculus (house mouse) ]

    Gene ID: 12651, updated on 25-May-2017
    Official Symbol
    Chkbprovided by MGI
    Official Full Name
    choline kinase betaprovided by MGI
    Primary source
    MGI:MGI:1328313
    See related
    Ensembl:ENSMUSG00000022617 Vega:OTTMUSG00000035435
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ck; Ek; Ckb; Chkl; Chetk; Ck/Ek; Ckekb; Ck/Ek-beta
    Orthologs
    Location:
    15; 15 E3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (89426349..89429927, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (89256798..89260330, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene synaptonemal complex central element protein 3 Neighboring gene predicted readthrough transcript (NMD candidate), 44502 Neighboring gene carnitine palmitoyltransferase 1b, muscle Neighboring gene uncharacterized LOC105246016 Neighboring gene mitogen-activated protein kinase 8 interacting protein 2

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1)  1 citation
    • Chemically induced (ENU) (1) 

    Markers

    Readthrough Gm44502

    Readthrough gene: Gm44502, Included gene: Cpt1b

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    choline kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    choline kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    ethanolamine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    glycerophospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    muscle organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphatidylcholine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phosphatidylethanolamine biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    choline/ethanolamine kinase
    Names
    choline/ethanolamine kinase-b
    choline/ethanolaminekinase
    ethanolamine kinase
    NP_031718.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007692.6NP_031718.1  choline/ethanolamine kinase

      See identical proteins and their annotated locations for NP_031718.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shortest transcript but encodes the supported protein.
      Source sequence(s)
      AC137513, AI853330, AK078101
      Consensus CDS
      CCDS27750.1
      UniProtKB/Swiss-Prot
      O55229
      UniProtKB/TrEMBL
      Q54AG5
      Related
      ENSMUSP00000023289.6, OTTMUSP00000049745, ENSMUST00000023289.12, OTTMUST00000090614
      Conserved Domains (2) summary
      PLN02236
      Location:57391
      PLN02236; choline kinase
      cd05156
      Location:73385
      ChoK_euk; Euykaryotic Choline Kinase

    RNA

    1. NR_037153.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) includes an extra segment in the central region, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC137513, AI853330
      Related
      ENSMUST00000170334.7
    2. NR_037154.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate internal splice site in the central region, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AC137513, AI853330

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      89426349..89429927 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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