U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Axud1 AXIN1 up-regulated 1 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33419, updated on 10-May-2024

    Summary

    Official Symbol
    Axud1provided by FlyBase
    Official Full Name
    AXIN1 up-regulated 1provided by FlyBase
    Primary source
    FLYBASE:FBgn0261647
    Locus tag
    Dmel_CG4272
    See related
    AllianceGenome:FB:FBgn0261647
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH09817; C676; CG4272; DAxud1; Dmel\CG4272
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of cell population proliferation. Located in nucleus. Is expressed in several structures, including cephalic furrow; germ band; imaginal disc; and presumptive embryonic/larval system. Orthologous to several human genes including CSRNP1 (cysteine and serine rich nuclear protein 1) and CSRNP2 (cysteine and serine rich nuclear protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Axud1 in Genome Data Viewer
    Location:
    22E1-22E1; 2-6 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2365345..2370137)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2365345..2370137)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene eyes shut Neighboring gene Rab5 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    AXIN1 up-regulated 1
    Names
    Axud1-PA
    Axud1-PB
    Axud1-PC
    Axud1-PD
    CG4272-PA
    CG4272-PB
    CG4272-PC
    CG4272-PD

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2365345..2370137
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272999.1NP_001259928.1  AXIN1 up-regulated 1, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259928.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G5, Q9VQB2
      Conserved Domains (2) summary
      PHA03255
      Location:643786
      PHA03255; BDLF3; Provisional
      pfam16019
      Location:301500
      CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
    2. NM_134829.3NP_608673.1  AXIN1 up-regulated 1, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608673.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G5, Q9VQB2
      Related
      FBpp0077442
      Conserved Domains (2) summary
      PHA03255
      Location:643786
      PHA03255; BDLF3; Provisional
      pfam16019
      Location:301500
      CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
    3. NM_164480.2NP_722800.1  AXIN1 up-regulated 1, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722800.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G5, Q9VQB2
      Related
      FBpp0077443
      Conserved Domains (2) summary
      PHA03255
      Location:643786
      PHA03255; BDLF3; Provisional
      pfam16019
      Location:301500
      CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus
    4. NM_001273000.1NP_001259929.1  AXIN1 up-regulated 1, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259929.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U4G5, Q9VQB2
      Conserved Domains (2) summary
      PHA03255
      Location:643786
      PHA03255; BDLF3; Provisional
      pfam16019
      Location:301500
      CSRNP_N; Cysteine/serine-rich nuclear protein N-terminus