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    UTP14C UTP14C, small subunit processome component [ Homo sapiens (human) ]

    Gene ID: 9724, updated on 2-Oct-2018

    Summary

    Official Symbol
    UTP14Cprovided by HGNC
    Official Full Name
    UTP14C, small subunit processome componentprovided by HGNC
    Primary source
    HGNC:HGNC:20321
    See related
    Ensembl:ENSG00000253797 MIM:608969; Vega:OTTHUMG00000164353
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UTP14B; KIAA0266; 2700066J21Rik
    Expression
    Ubiquitous expression in thyroid (RPKM 12.7), kidney (RPKM 9.1) and 25 other tissues See more
    Orthologs

    Genomic context

    See UTP14C in Genome Data Viewer
    Location:
    13q14.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 13 NC_000013.11 (52024691..52033600)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (52598827..52607736)

    Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene CTAGE family member 3, pseudogene Neighboring gene ATPase copper transporting beta Neighboring gene fatty acid binding protein 5 pseudogene 2 Neighboring gene ALG11, alpha-1,2-mannosyltransferase Neighboring gene NIMA related kinase 5 Neighboring gene NIMA related kinase 5 Neighboring gene uncharacterized LOC101929657

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Gene Expression, organism-specific biosystem (from REACTOME)
      Gene Expression, organism-specific biosystemGene Expression covers the pathways by which genomic DNA is transcribed to yield RNA, the regulation of these transcription processes, and the pathways by which newly-made RNA Transcripts are process...
    • Major pathway of rRNA processing in the nucleolus and cytosol, organism-specific biosystem (from REACTOME)
      Major pathway of rRNA processing in the nucleolus and cytosol, organism-specific biosystemIn humans, a 47S precursor rRNA (pre-rRNA) is transcribed by RNA polymerase I from rRNA-encoding genes (rDNA) at the boundary of the fibrillar center and the dense fibrillar components of the nucleol...
    • Ribosome biogenesis in eukaryotes, organism-specific biosystem (from KEGG)
      Ribosome biogenesis in eukaryotes, organism-specific biosystemRibosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It...
    • Ribosome biogenesis in eukaryotes, conserved biosystem (from KEGG)
      Ribosome biogenesis in eukaryotes, conserved biosystemRibosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It...
    • rRNA modification in the nucleus and cytosol, organism-specific biosystem (from REACTOME)
      rRNA modification in the nucleus and cytosol, organism-specific biosystemHuman ribosomal RNAs (rRNAs) contain about 200 residues that are enzymatically modified after transcription in the nucleolus (Maden and Khan 1977, Maden 1988, Maden and Hughes 1997, reviewed in Herna...
    • rRNA processing, organism-specific biosystem (from REACTOME)
      rRNA processing, organism-specific biosystemEach eukaryotic cytosolic ribosome contains 4 molecules of RNA: 28S rRNA (25S rRNA in yeast), 5.8S rRNA, and 5S rRNA in the 60S subunit and 18S rRNA in the 40S subunit. The 18S rRNA, 5.8S rRNA, and 2...
    • rRNA processing in the nucleus and cytosol, organism-specific biosystem (from REACTOME)
      rRNA processing in the nucleus and cytosol, organism-specific biosystemEach eukaryotic cytosolic ribosome contains 4 molecules of RNA: 28S rRNA (25S rRNA in yeast), 5.8S rRNA, and 5S rRNA in the 60S subunit and 18S rRNA in the 40S subunit. The 18S rRNA, 5.8S rRNA, and 2...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC104971

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytosol IDA
    Inferred from Direct Assay
    more info
     
    nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleolus IDA
    Inferred from Direct Assay
    more info
     
    small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    U3 small nucleolar RNA-associated protein 14 homolog C
    Names
    UTP14, U3 small nucleolar ribonucleoprotein, homolog C
    UTP14, small subunit processome component homolog C

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021645.5NP_067677.4  U3 small nucleolar RNA-associated protein 14 homolog C

      See identical proteins and their annotated locations for NP_067677.4

      Status: VALIDATED

      Source sequence(s)
      AI076921, BC089407, D87455, N71815
      Consensus CDS
      CCDS31978.1
      UniProtKB/Swiss-Prot
      Q5TAP6
      UniProtKB/TrEMBL
      A0A024RDV0
      Related
      ENSP00000428619.1, OTTHUMP00000018445, ENST00000521776.2, OTTHUMT00000045049
      Conserved Domains (2) summary
      pfam01056
      Location:369458
      Myc_N; Myc amino-terminal region
      pfam04615
      Location:28732
      Utp14; Utp14 protein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000013.11 Reference GRCh38.p12 Primary Assembly

      Range
      52024691..52033600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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