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    RLM1 Rlm1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856016, updated on 17-May-2024

    Summary

    Gene symbol
    RLM1
    Gene description
    Rlm1p
    Primary source
    FungiDB:YPL089C
    Locus tag
    YPL089C
    See related
    SGD:S000006010; AllianceGenome:SGD:S000006010; VEuPathDB:YPL089C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA binding activity, bending; DNA-binding transcription factor activity, RNA polymerase II-specific; and sequence-specific DNA binding activity. Involved in several processes, including positive regulation of transcription from RNA polymerase II promoter in response to stress; regulation of G1 to G0 transition; and regulation of flocculation. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20 and dilated cardiomyopathy. Orthologous to several human genes including MEF2A (myocyte enhancer factor 2A); MEF2C (myocyte enhancer factor 2C); and MEF2D (myocyte enhancer factor 2D). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See RLM1 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (379120..381150, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene glutathione-disulfide reductase GLR1 Neighboring gene ribosomal 40S subunit protein S6A Neighboring gene aldo-keto reductase superfamily protein Neighboring gene alkaline dihydroceramidase

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Rlm1p
    NP_015236.1
    • MADS-box transcription factor; component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; RLM1 has a paralog, SMP1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      379120..381150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183903.1NP_015236.1  TPA: Rlm1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015236.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3S8, Q12224
      UniProtKB/TrEMBL
      A0A6A5Q108, G2WP92, N1NVX2
      Conserved Domains (2) summary
      COG5068
      Location:146673
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:277
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...