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    PIG2 putative protein phosphatase regulator PIG2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854766, updated on 17-May-2024

    Summary

    Gene symbol
    PIG2
    Gene description
    putative protein phosphatase regulator PIG2
    Primary source
    FungiDB:YIL045W
    Locus tag
    YIL045W
    See related
    SGD:S000001307; AllianceGenome:SGD:S000001307; VEuPathDB:YIL045W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable glycogen binding activity; protein phosphatase 1 binding activity; and protein phosphatase regulator activity. Involved in regulation of glycogen biosynthetic process. Located in cytoplasm. Orthologous to several human genes including PPP1R3B (protein phosphatase 1 regulatory subunit 3B); PPP1R3C (protein phosphatase 1 regulatory subunit 3C); and PPP1R3D (protein phosphatase 1 regulatory subunit 3D). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See PIG2 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (271161..272777)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ubiquitin-binding SDF ubiquitin ligase complex subunit MET30 Neighboring gene GTPase-activating protein AGE2 Neighboring gene cytochrome-b5 reductase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables glycogen binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein phosphatase 1 binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein phosphatase regulator activity ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of glycogen biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of glycogen biosynthetic process IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    part_of protein phosphatase type 1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative protein phosphatase regulator PIG2
    NP_012219.3
    • Putative type-1 protein phosphatase targeting subunit; tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase; PIG2 has a paralog, GIP2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      271161..272777
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179395.3NP_012219.3  TPA: putative protein phosphatase regulator PIG2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012219.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVN7, E9P960, P40187
      UniProtKB/TrEMBL
      A0A8H4C0A4, A6ZVM4, B3LTQ1, B5VKQ2, N1P950
      Conserved Domains (1) summary
      pfam03370
      Location:388508
      CBM_21; Carbohydrate/starch-binding module (family 21)